1 Result for "

PFN-α

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PFN-α" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-123076
CAS No.: 60477-38-5
Purity:  99.37%
Synonyms: PFN
Target:  

MDM-2/p53

Research Areas:  

Neurological Disease

Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED50=30 nM). Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue .
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