1 Result for "

PIM-1/HDAC-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PIM-1/HDAC-IN-1" in MCE Product Catalog:

Cat. No.: HY-143233
CAS No.: 2897622-19-2
Target:  

Pim HDAC Apoptosis

Research Areas:  

Cancer

PIM-1/HDAC-IN-1 (compound 4d) is a PIM-1 inhibitor, with an IC50 of 343.87 nM. PIM-1/HDAC-IN-1 has strong inhibitory activity and selectivity against HDAC 1 and HDAC 6, with IC50 values of 63.65 and 62.39 nM, respectively. PIM-1/HDAC-IN-1 exhibits apoptosis inducing potential in MCF-7 cell lines. PIM-1/HDAC-IN-1 shows pre-G1 apoptosis and cell cycle arrest at G2/M phase [1].
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