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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
PROTAC OSBP Degrader-1
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "PROTAC OSBP Degrader-1" in MCE Product Catalog:
Cat. No.: HY-178034
Research Areas:
PROTAC OSBP Degrader-1 (Compound 5) is a Oxysterol-binding protein (OSBP) PROTAC degrader with a DC50 of 322 nM (24 h). PROTAC OSBP Degrader-1 can rapidly penetrate into cells and induce massive recruitment of OSBP at the Trans-Golgi network. PROTAC OSBP Degrader-1 has potent anticancer activity with potent cytotoxicity against U-87 MG, A549, MCF7, HeLa and MDA-MB-231 cells . Pink: OSBP ligand (HY-178035); Blue: CRBN ligase ligand (HY-10984); Black: linker
Cat. No.: HY-178035
CAS No.: 2890760-73-1
Research Areas:
OSBP ligand-1 (Compound 2) is an Oxysterol-binding protein (OSBP) inhibitor. OSBP ligand-1 can be used for synthesis of PROTAC OSBP Degrader-1 (HY-178034) .
Cat. No.: HY-178046
Research Areas:
OSBP ligand-Linker Conjugate 1 is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for OSBP (HY-178035) and a PROTAC linker, which recruits E3 ligases. OSBP ligand-Linker Conjugate 1 can be used for synthesis of PROTAC OSBP Degrader-1 (HY-178034) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
