2 Results for "

PROTAC TYK2 degrader-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PROTAC TYK2 degrader-1" in MCE Product Catalog:

Cat. No.: HY-158142
CAS No.: 2770470-20-5
Purity:  99.46%
Target:  

PROTACs JAK STAT

Research Areas:  

Inflammation/Immunology Cancer

PROTAC TYK2 degrader-1 is a TYK2 PROTAC degrader with a Dmax ≥ 60%. PROTAC TYK2 degrader-1 reduces the phosphorylation levels of IFNα-induced STAT1 (Tyr701) and STAT3 (Tyr705) in immune cells. PROTAC TYK2 degrader-1 can be used in research on cancer, inflammatory diseases, etc.
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Cat. No.: HY-174430
CAS No.: 1558007-80-9
Research Areas:  

Cancer

WWQ-131 is a potent selective JAK2 inhibitor with an IC50 of 2.56 nM. WWQ-131 shows >252-fold selectivity over JAK1, JAK3, and TYK2. WWQ-131 exhibits antiproliferative activity against cancer cells. WWQ-131 is the ligand for target protein for PROTAC JAK2 degrader-1 (HY-174428). WWQ-131 can be used for the research of myeloproliferative neoplasms (MPNs) .
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