Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
PbI 2
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "PbI 2" in MCE Product Catalog:
6
Target:
1
1 Cited Publications
Synonyms: Setogepram sodium; PbI-4050 sodium
Target:
Research Areas:
Fezagepras (Setogepram) sodium acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84 . Fezagepras sodium decreases renal, liver and pancreatic fibrosis [2]. Fezagepras sodium exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions [2].
1
1 Cited Publications
Synonyms: Setogepram; PbI-4050
Target:
Research Areas:
Fezagepras (Setogepram) acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84 . Fezagepras decreases renal, liver and pancreatic fibrosis [2]. Fezagepras exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions [2].
1
Pomotrelvir is a selective, competitive, orally active covalent inhibitor of the SARS-CoV-2 main protease (M pro), with an IC50 of 24 nM for wild-type SARS-CoV-2 M pro. Pomotrelvir inhibits viral polyprotein processing, thereby preventing viral replication. Pomotrelvir has shown broad antiviral activity against multiple SARS-CoV-2 variants (including Omicron) in cell-based experiments, and has an additive effect when combined with nucleoside analogs that target viral RNA synthesis. Pomotrelvir is primarily used for the research and development of COVID-19 antiviral drugs, especially for infections caused by SARS-CoV-2 and its variants [2].
Target:
Research Areas:
Bis-PEG4-NHS ester is a crosslinking reagent and amine-reactive modulator [2].Bis-PEG4-NHS ester reacts with primary amine groups on liposome surfaces via amide bond formation to covalently attach dibenzylcyclooctyne groups, with a hydrophilic PEG4 spacer reducing steric hindrance for subsequent click chemistry .Bis-PEG4-NHS ester enables site-specific antibody coupling to liposome surfaces via copper-free strain-promoted alkyne-azide cycloaddition click chemistry without disrupting liposome structure in minimal organic solvent volumes .Bis-PEG4-NHS ester undergoes hydrolysis during annealing to form -COOH groups that interact with PbI and FAI to enhance perovskite structural integrity, passivate defects, and modulate nucleation kinetics to regulate crystal growth [2].Bis-PEG4-NHS ester enhances device efficiency and long-term stability when used as an antisolvent additive for p-i-n perovskite solar cells [2].
Synonyms: PbI-200; PPI-5278
Target:
Research Areas:
Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases .
Cat. No.: HY-W016414
CAS No.: 78-40-0
Research Areas:
Triethyl phosphate is a versatile phosphate ester compound. Triethyl phosphate induces rapid and short-acting anesthesia, and exhibits hypotensive, smooth muscle relaxant, and cardiac inhibitory effects. Triethyl phosphate also modulates cholinergic toxicity; its anesthetic effect shows sex- and age-dependency in rodents, and it interacts with SKF 525-A (HY-B1311) to alter the duration of anesthesia [2].
Cat. No.: HY-150723
CAS No.: 2857098-72-5
Target:
Research Areas:
PBI-6DNJ is an orally active and potent multivalent glycosidase inhibitor. PBI-6DNJ exhibits good inhibition activity against α-glucosidase from mice, with a Ki of 0.14 μM. PBI-6DNJ exhibits good hypoglycemic activity. PBI-6DNJ can be used for type 2 diabetes research .
Cat. No.: HY-N11060
CAS No.: 15764-81-5
Synonyms: PbI 344
Target:
Cat. No.: HY-123568
CAS No.: 175072-12-5
Synonyms: BCH-1393
Target:
Research Areas:
PBI-1393 (BCH-1393) is an anticancer agent that enhances Th1 type cytokine production and primary T cell activation .
Category:
Target:
Cat. No.: HY-100775AR
CAS No.: 1002101-19-0
Synonyms: Setogepram (Standard); PbI-4050 (Standard)
Research Areas:
Fezagepras (Standard) is the analytical standard of Fezagepras. This product is intended for research and analytical applications. Fezagepras (Setogepram) acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84 . Fezagepras decreases renal, liver and pancreatic fibrosis [2]. Fezagepras exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions [2].
Cat. No.: HY-100775R
CAS No.: 1254472-97-3
Synonyms: Setogepram sodium (Standard); PbI-4050 sodium (Standard)
Research Areas:
Fezagepras (sodium) (Standard) is the analytical standard of Fezagepras (sodium). This product is intended for research and analytical applications. Fezagepras (Setogepram) sodium acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84 . Fezagepras sodium decreases renal, liver and pancreatic fibrosis [2]. Fezagepras sodium exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions [2].
Cat. No.: HY-N11060A
CAS No.: 7070-24-8
Synonyms: (±)-PbI 344
Category:
Target:
Cat. No.: HY-P703065
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PbI-SS(Tom)(TP)101-EGFP; other Blue Fluorescent Protein
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
