2353522-15-1

Paltimatrectinib Chemical Structure
2353522-15-1

Chemical Structure

Paltimatrectinib

Synonym(s): PBI-200; PPI-5278

  • CAS No.: 2353522-15-1
  • Formula:C20H15F5N6
  • Molecular Weight:434.37

IUPAC Name: (R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-(4-(trifluoromethyl)-1H-pyrazol-1-yl)pyrazolo[1,5-a]pyrimidine

InChIKey: FYPXPQSPRRZJCK-MRXNPFEDSA-N

SMILES: FC(F)(C1=CN(N=C1)C2=C3N(C=CC(N4[C@](C5=C(C=CC(F)=C5)F)([H])CCC4)=N3)N=C2)F

Biological Activity: Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases[1].

Cat. No. Product Name Purity Description Pricing
HY-145587 		Paltimatrectinib 99.95% Paltimatrectinib (compound I-147) is a potent tyrosine kinase inhibitor with an IC50 of <10 nM for tropomyosin kinases A (TrkA). Paltimatrectinib has the potential for cancer and inflammatory diseases.
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