1 Result for "

Periplogenin (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Periplogenin (Standard)" in MCE Product Catalog:

Periplogenin (Standard)
Periplogenin (Standard)
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Cat. No.: HY-N2414R
CAS No.: 514-39-6
Category:  

other families Plants Steroids

Target:  

Reference Standards Reactive Oxygen Species (ROS) Necroptosis Pyroptosis Interleukin Related Caspase NOD-like Receptor (NLR)

Periplogenin (Standard) is the analytical standard of Periplogenin (HY-N2414). Periplogenin is an orally active cardiac glycoside found in Cortex periplocae. Periplogenin can induce ROS production and necroptosis and cause G0/G1 phase arrest. Periplogenin can inhibit pyroptosis by regulating the NLRP3/Caspase-1/GSDMD signaling. Periplogenin suppresses growth of prostate carcinoma cells by docking to an ATP1A1 protein pocket and forming a hydrogen bond with T804. Periplogenin can be used for the researches of cancer, inflammation and immunology, such as prostate carcinoma, rheumatoid arthritis and psoriasis .
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