Search Result

Results for "

Phe-Gly

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Linker (16) Amino Acid Derivatives (3) Angiotensin-converting Enzyme (ACE) (1) Antibody-Drug Conjugates (ADCs) (4) Apoptosis (1) Bacterial (2) Biochemical Assay Reagents (5) Drug Intermediate (3) Drug-Linker Conjugates for ADC (16) EGFR (2) Endogenous Metabolite (1) Influenza Virus (1) Isotope-Labeled Compounds (1) mTOR (1) Mucin (1) Neurokinin Receptor (2) PI3K (1) PROTAC Linkers (2) Reference Standards (1) Ser/Thr Protease (1) Topoisomerase (10)
By Research Areas:	Cancer (37) Infection (3) Metabolic Disease (1) Neurological Disease (2)

By Targets:

ADC Linker (16)

Amino Acid Derivatives (3)

Angiotensin-converting Enzyme (ACE) (1)

Antibody-Drug Conjugates (ADCs) (4)

Apoptosis (1)

Bacterial (2)

Biochemical Assay Reagents (5)

Drug Intermediate (3)

Drug-Linker Conjugates for ADC (16)

EGFR (2)

Endogenous Metabolite (1)

Influenza Virus (1)

Isotope-Labeled Compounds (1)

mTOR (1)

Mucin (1)

Neurokinin Receptor (2)

PI3K (1)

PROTAC Linkers (2)

Reference Standards (1)

Ser/Thr Protease (1)

Topoisomerase (10)

By Research Areas:

Cancer (37)

Infection (3)

Metabolic Disease (1)

Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

GMP Molecules

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-148668

*MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan* SHR-A1811 Drug-linker	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC₅₀=2.2 μM) .

HY-147164

*MC-Gly-Gly-Phe-Gly-PAB-PNP*	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for synthesis anti-human EGFR antibody agent conjugate .

HY-44246

MC-Gly-Gly-Phe-Gly 2 Publications Verification Mc-GGFG-OH	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-W010991

*N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly* 1 Publications Verification FAPGG	Angiotensin-converting Enzyme (ACE)	Others
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a specific substrate of angiotensin converting enzyme (ACE) with a Ki of 2.546×10 ^-4 M. It is used as a chromogenic probe for quantitative detection of ACE activity. N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly can be hydrolyzed by ACE to generate N-[3-(2-furyl)acryloyl]-Phe (FAP) and Gly-Gly, and the ACE inhibitory effect is monitored by photometry. FAPGG competitively binds to the active center of ACE and is a key tool for screening ACE inhibitors such as Captopril (HY-B0368) and Dioscorin. Its reversible mechanism of action supports hypertension research and drug development targeting the renin-angiotensin system .

HY-131990

*MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH*	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P3669

Gly-Gly-Phe-Gly	ADC Linker Drug Intermediate	Cancer
Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689) .

HY-P1449

*Boc-Gly-Gly-Phe-Gly-OH*	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-45672

*Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH*	ADC Linker	Cancer
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

HY-P4192

*Fomc-Gly-Gly-Phe-Gly-OH*	ADC Linker	Cancer
Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .

HY-13631M

*Gly-Gly-Phe-Gly-NH-O-CO-Exatecan*	Drug-Linker Conjugates for ADC	Cancer
Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a Drug-Linker Conjugates for ADC, consiting of an ADC linker and Exatecan (HY-13631) (topoisomerase I inhibitor). Gly-Gly-Phe-Gly-NH-O-CO-Exatecan can be used for ADC molecues synthesis.

HY-177442

DS-3939a DS-3939	Antibody-Drug Conjugates (ADCs) Mucin Topoisomerase Apoptosis	Cancer
DS-3939a (DS-3939) is an anti-TA-MUC1 (tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1 IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .

HY-136432

*Mc-Gly-Gly-Phe-Gly-PAB-OH* Mc-GGFG-PAB-OH	ADC Linker	Cancer
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-W141936

*Phe-Gly* L-PhenylalanylGlycine; H-Phe-Gly-OH	Amino Acid Derivatives	Others
Phe-Gly hydrate is a Glycine (HY-Y0966) derivative .

HY-45545

*Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH*	Drug Intermediate	Others
Fmoc-gly-gly-ph-gly-nh-ch2-o-ch2cooh can be used to synthesize the ADC Linker, LND1067 .

HY-13631F

*Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research .

HY-153795

*Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is a bioactive drug-linker conjugate for ADC (Drug-Linker Conjugates for ADC). Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan consists of Exatecan (HY-13631) and a linker. Mal-PEG2-Gly-Gly-Phe-Gly-Exatecan is applicable to ADC synthesis and cancer research. Exatecan acts as a DNA Topoisomerase I inhibitor .

HY-49412

*Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3*	Drug Intermediate	Others
Fmoc-Gly-Gly-Phe-Gly-NH-CH2-O-CO-CH3 (compound DC-13-C) is an intermediate in the synthesis of Exatecan (HY-13631) derivatives .

HY-164762

Trastuzumab rezetecan SHR-A1811	Antibody-Drug Conjugates (ADCs) EGFR	Cancer
Trastuzumab rezetecan (SHR-A1811) is a HER2-targeting antibody-drug conjugate (ADC). Trastuzumab rezetecan is composed of a humanized anti-HER2 antibody (HY-P9907), a cleavable linker MC-Gly-Gly-Phe-Gly (HY-44246), and a topoisomerase I inhibitor payload Rezetecán (HY-147408). Trastuzumab rezetecan can be used for research in HER2-positive breast cancer .

HY-148668A

*MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC₅₀=2.2 μM) .

HY-147307

*MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is a agent-linker conjugate for ADC, contains the ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan synthesized ADC can be used in study of cancer .

HY-W048829

*Boc-Phe-Gly-OH*	Amino Acid Derivatives	Others
Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .

HY-132134

*MC-Gly-Gly-Phe-Gly-PAB-MMAE*	Biochemical Assay Reagents	Cancer
MC-Gly-Gly-Phe-Gly-PAB-MMAE (Compound SMP-81641) is a control targeted linker-agent conjugate. MC-Gly-Gly-Phe-Gly-PAB-MMAE can be used in tumor research .

HY-150402

*MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan is a pharmaceutical composition containing antibody agent conjugate (ADC). (extracted from patent WO2021190581 Example 1-8) .

HY-W295873

*Cyclo(Phe-Gly)* 1 Publications Verification	Bacterial	Infection Cancer
Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis .

HY-153067

*Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan (Compound 11) is a bioactive compound-linker conjugate for ADC. Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan can conjugate with antibodies to form ADC (C-11) with anti-tumor activity. Exatecan is a DNA Topoisomerase I inhibitor. Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan can be used in the research of squamous cell carcinoma, pancreatic adenocarcinoma and colorectal cancer .

HY-160649

*MC-Gly-Gly-Phe-Gly-GABA-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
MC-Gly-Gly-Phe-Gly-GABA-Exatecan is an agent linker conjugate for ADC, with an inhibitor for Topoisomerase Exatecan (HY-13631) with IC₅₀ of 22 μM. MC-Gly-Gly-Phe-Gly-GABA-Exatecan targets various antibodies, exhibits cytotoxic and antitumor efficacy in vitro and in vivo .

HY-45669

*Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz*	PROTAC Linkers	Cancer
Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .

HY-W017692

2-Aminoindan-2-phosphonic acid hydrochloride 1 Publications Verification	Biochemical Assay Reagents	Metabolic Disease
2-Aminoindan-2-phosphonic acid hydrochloride is a competitive phenylalanine ammonia lyase (PAL) inhibitor that significantly decreases the levels of total phenolic compounds and PheGs in plant cultured cells .

HY-49057

*MC-Gly-Gly-Phe-Gly-cyclopropylacetic acid*	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly-cyclopropylacetic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-P1449A

*Boc-Gly-Gly-Phe-Gly-OH TFA*	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-136432A

*Mc-Gly-Gly-Phe-Gly-PAB-OH TFA* Mc-GGFG-PAB-OH TFA	ADC Linker	Cancer
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-P3885

Substance P (alligator)	Neurokinin Receptor Endogenous Metabolite	Neurological Disease
Substance P (alligator), a Substance P (HY-P0201) extracted from alligator, is a neuropeptide. The primary structure of Substance P (alligator) is: Arg-Pro-Arg-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 .

HY-177711

Tizetatug rezetecan SHR-A1921	Antibody-Drug Conjugates (ADCs)	Cancer
Tizetatug rezetecan (SHR-A1921) is an Antibody-drug Conjugate (ADC) composed of antibody Tizetatug (HY-P991032) and MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (HY-148668). Tizetatug rezetecan can be used for the research of cancer .

HY-148812

*Gly-Mal-Gly-Gly-Phe-Gly-amide-methylcyclopropane-Exatecan*	Drug-Linker Conjugates for ADC Topoisomerase	Cancer
Gly-Mal-Gly-Gly-Phe-Gly-amide-methylcyclopropane-Exatecan is used for ADC Synthesis .

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-131990A

*MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH*	ADC Linker	Cancer
MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-114437

Fusion Inhibitory Peptide Z-D-Phe-Phe-Gly-OH; FIP; Virus Replication Inhibitory Peptide	Influenza Virus	Infection
Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) is a potent inhibitor of the virus replication, by inhibiting the membrane fusing activity of a viral glycoprotein .

HY-178146

Mc-Lys(PEG12)-Cap-Ala-Ala-PABC	ADC Linker	Cancer
Mc-Lys(PEG12)-Cap-Ala-Ala-PABC is a linker of MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (HY-178146) .

HY-148415

*Ac-Phe-Gly-pNA*	Ser/Thr Protease	Others
Ac-Phe-Gly-pNA is the chymotrypsin specific substrate .

HY-P4556

*H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe*	Biochemical Assay Reagents	Others
H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .

HY-49453

*Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz*	PROTAC Linkers	Cancer
Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	ADC Linker	Cancer
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

HY-160453

*MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH*	Drug-Linker Conjugates for ADC	Others
MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH is a camptothecin derivative. MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH can be used for antibody drug conjugate (ADC) .

HY-131990S

*MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d5*	Isotope-Labeled Compounds	Others
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d₅ is deuterated labeled MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH .

HY-160683

*MC-Gly-Gly-Phe-Gly-NH-CH2-O-amide-Eribulin*	Drug-Linker Conjugates for ADC	Cancer
MC-Gly-Gly-Phe-Gly-NH-CH2-O-amide-Eribulin (Compound 7) can be used as a linker-drug intermediate for the synthesis of antibody-drug conjugates (ADCs) .

HY-120522

L-659877 Cyclo(Gln-Trp-Phe-Gly-Leu-Met)	Neurokinin Receptor	Others
L-659877 (Cyclo(Gln-Trp-Phe-Gly-Leu-Met)) is a compound used to study the chemical properties of peptide fragments in collision-induced dissociation. A series of experiments were conducted to study the structural changes of b-fragment ions of different lengths in collision-induced dissociation.

HY-49463

*Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Gly-CH2-O-CH2-Cbz*	ADC Linker	Neurological Disease
Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Gly-CH2-O-CH2-Cbz is an ADC linker that can be used in the synthesis of ADCs (such as Trastuzumab deruxtecan and U3-1402).

HY-W009345

L-Phenylalanylglycylglycine Phe-Gly-Gly; H-Phe-Gly-Gly-OH	Amino Acid Derivatives	Others
L-Phenylalanylglycylglycine is a Glycine (HY-Y0966) derivative .

HY-W295873R

*Cyclo(Phe-Gly) (Standard)*	Bacterial Reference Standards	Infection Cancer
Cyclo(Phe-Gly) (Standard) is the analytical standard of Cyclo(Phe-Gly) (HY-W295873). This product is intended for research and analytical applications. Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis .

HY-181429

*Fmoc-Gly-Gly-Phe-Gly-Paclitaxel*	Drug-Linker Conjugates for ADC	Cancer
Fmoc-Gly-Gly-Phe-Gly-Paclitaxel (Compound 16a-3) is a drug-linker conjugates for ADC. Fmoc-Gly-Gly-Phe-Gly-Paclitaxel contains the ADC linker Fmoc-Gly-Gly-Phe-OH (HY-131833) and a potent tubulin polymerization inhibitor Paclitaxel (HY-B0015). Fmoc-Gly-Gly-Phe-Gly-Paclitaxel can be used for the research of cancer .

Cat. No.	Product Name	Type

HY-W010991

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly

1 Publications Verification

FAPGG

Fluorescent Dyes

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a specific substrate of angiotensin converting enzyme (ACE) with a Ki of 2.546×10 ^-4 M. It is used as a chromogenic probe for quantitative detection of ACE activity. N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly can be hydrolyzed by ACE to generate N-[3-(2-furyl)acryloyl]-Phe (FAP) and Gly-Gly, and the ACE inhibitory effect is monitored by photometry. FAPGG competitively binds to the active center of ACE and is a key tool for screening ACE inhibitors such as Captopril (HY-B0368) and Dioscorin. Its reversible mechanism of action supports hypertension research and drug development targeting the renin-angiotensin system .

HY-177442

DS-3939a

DS-3939

Fluorescent Dyes

DS-3939a (DS-3939) is an anti-TA-MUC1 (tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1 IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .

HY-164762

Trastuzumab rezetecan SHR-A1811	Fluorescent Dyes
Trastuzumab rezetecan (SHR-A1811) is a HER2-targeting antibody-drug conjugate (ADC). Trastuzumab rezetecan is composed of a humanized anti-HER2 antibody (HY-P9907), a cleavable linker MC-Gly-Gly-Phe-Gly (HY-44246), and a topoisomerase I inhibitor payload Rezetecán (HY-147408). Trastuzumab rezetecan can be used for research in HER2-positive breast cancer .

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	Fluorescent Dyes
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	Fluorescent Dyes
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

HY-160453

*MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH*	Fluorescent Dyes
MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH is a camptothecin derivative. MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH can be used for antibody drug conjugate (ADC) .

Cat. No.	Product Name	Type

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	Biochemical Assay Reagents
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	Biochemical Assay Reagents
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

Cat. No.	Product Name	Target	Research Area

HY-W010991

*N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly* 1 Publications Verification FAPGG	Angiotensin-converting Enzyme (ACE)	Others
N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a specific substrate of angiotensin converting enzyme (ACE) with a Ki of 2.546×10 ^-4 M. It is used as a chromogenic probe for quantitative detection of ACE activity. N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly can be hydrolyzed by ACE to generate N-[3-(2-furyl)acryloyl]-Phe (FAP) and Gly-Gly, and the ACE inhibitory effect is monitored by photometry. FAPGG competitively binds to the active center of ACE and is a key tool for screening ACE inhibitors such as Captopril (HY-B0368) and Dioscorin. Its reversible mechanism of action supports hypertension research and drug development targeting the renin-angiotensin system .

HY-P3669

Gly-Gly-Phe-Gly	ADC Linker Drug Intermediate	Cancer
Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates. Gly-Gly-Phe-Gly can be used as an ADC linker to synthesize ADCs, such as Puxitatug samrotecan (AZD 8205) (HY-171689) .

HY-P1449

*Boc-Gly-Gly-Phe-Gly-OH*	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-P4192

*Fomc-Gly-Gly-Phe-Gly-OH*	ADC Linker	Cancer
Fomc-Gly-Gly-Phe-Gly-OH (compound D5) can be used as an intermediate in the synthesis of ADC dual-drug-linker. Fomc-Gly-Gly-Phe-Gly-OH synthetic intermediate GGFGE further forms an important ADC dual-drug link assembly unit .

HY-136432

*Mc-Gly-Gly-Phe-Gly-PAB-OH* Mc-GGFG-PAB-OH	ADC Linker	Cancer
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-W141936

*Phe-Gly* L-PhenylalanylGlycine; H-Phe-Gly-OH	Amino Acid Derivatives	Others
Phe-Gly hydrate is a Glycine (HY-Y0966) derivative .

HY-W048829

*Boc-Phe-Gly-OH*	Amino Acid Derivatives	Others
Boc-Phe-Gly-OH is a Boc-protected phenylalanyl glycine derivative, can be used for the synthesis of agents or other compounds .

HY-P1449A

*Boc-Gly-Gly-Phe-Gly-OH TFA*	ADC Linker	Cancer
Boc-Gly-Gly-Phe-Gly-OH TFA, a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC).

HY-136432A

*Mc-Gly-Gly-Phe-Gly-PAB-OH TFA* Mc-GGFG-PAB-OH TFA	ADC Linker	Cancer
Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

HY-P3885

Substance P (alligator)	Neurokinin Receptor Endogenous Metabolite	Neurological Disease
Substance P (alligator), a Substance P (HY-P0201) extracted from alligator, is a neuropeptide. The primary structure of Substance P (alligator) is: Arg-Pro-Arg-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 .

HY-114437

Fusion Inhibitory Peptide Z-D-Phe-Phe-Gly-OH; FIP; Virus Replication Inhibitory Peptide	Influenza Virus	Infection
Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) is a potent inhibitor of the virus replication, by inhibiting the membrane fusing activity of a viral glycoprotein .

HY-P4251

*Gly-Phe-Gly-Aldehyde semicarbazone*	Peptides	Others
Gly-Phe-Gly-Aldehyde semicarbazone is a peptide.

HY-P4556

*H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe*	Biochemical Assay Reagents	Others
H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is a polypeptide that can be hydrolyzed by Rennin (HY-P2810). H-Phe-Gly-His-p-nitro-Phe-Phe-Ala-Phe-OMe is commonly used as a biochemical reaction reagent .

HY-W009345

L-Phenylalanylglycylglycine Phe-Gly-Gly; H-Phe-Gly-Gly-OH	Amino Acid Derivatives	Others
L-Phenylalanylglycylglycine is a Glycine (HY-Y0966) derivative .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W295873

*Cyclo(Phe-Gly)* 1 Publications Verification	Infection Natural Products Classification of Application Fields Plants Compositae Disease Research Fields Source Classification Gueldenstaedtia verna (Georgi) Boriss. Cancer	Bacterial
Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis .

HY-W295873R

*Cyclo(Phe-Gly) (Standard)*	Structural Classification Natural Products Plants Compositae Source Classification Gueldenstaedtia verna (Georgi) Boriss.	Bacterial Reference Standards
Cyclo(Phe-Gly) (Standard) is the analytical standard of Cyclo(Phe-Gly) (HY-W295873). This product is intended for research and analytical applications. Cyclo(Phe-Gly) is a cyclodipeptides with antimicrobial and anticancer activities, isolated from broth culture of endophytic Streptomyces YIM 64018 associated with Paraboea sinensis .

Cat. No.	Product Name	Chemical Structure

HY-131990S

*MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d5*
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH-d₅ is deuterated labeled MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH .

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-131990G

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	ADC Linker	Cancer
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-131990). MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-45672G

Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH	ADC Linker	Cancer
Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH GMP is a GMP grade Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH (HY-45672). Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate .

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Phe-Gly

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