2414254-51-4
2414254-51-4
Chemical Structure
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
Synonym(s): SHR-A1811 Drug-linker
- CAS No.: 2414254-51-4
- Formula:C55H60FN9O13
- Molecular Weight:1074.12
IUPAC Name: ethyl (4R,5R)-4,5-dimethyl-3-oxo-5-(trifluoromethyl)tetrahydrofuran-2-carboxylate
InChIKey: WKCCHLIWLNJSMH-ZDPDOTMZSA-N
SMILES: O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCO[C@H](C3CC3)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O)=O
Biological Activity: MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan | 95.08% | MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan (SHR-A1811 Drug-linker) is a agent-linker conjugates for ADC, consisting Exatecan (HY-13631). Exatecan is a DNA Topoisomerase I inhibitor (IC50=2.2 μM). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
