1 Result for "

Pipinib

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Pipinib" in MCE Product Catalog:

Cat. No.: HY-182721
CAS No.: 2380013-55-6
Target:  

PI4K Hedgehog

Research Areas:  

Cancer

Pipinib is an ATP-competitive and selective phosphatidylinositol 4-kinase IIIb (PI4KB) inhibitor with an IC50 of 2.2 μM. Pipinib reduces intracellular PI4P levels. Pipinib inhibits GLI-mediated transcription, the expression of Hedgehog target genes, and blocks the trafficking of Smoothened to cilia. Pipinib can be used in the research of basal cell carcinoma and medulloblastoma .
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