26 Results for "

RMI

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "RMI" in MCE Product Catalog:

23
23 Publications Verification
Cat. No.: HY-B0744
CAS No.: 70052-12-9
Synonyms: DFMO; MDL71782; RMI71782; α-difluoromethylornithine
Target:  

Parasite

Research Areas:  

Infection Cancer

Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
loading...
    loading...
23
23 Publications Verification
Cat. No.: HY-B0744B
CAS No.: 96020-91-6
Synonyms: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate
Target:  

Parasite

Research Areas:  

Cancer

Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .
loading...
    loading...
23
23 Publications Verification
Cat. No.: HY-B0744A
CAS No.: 68278-23-9
Synonyms: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride
Target:  

Parasite

Research Areas:  

Infection Cancer

Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
loading...
    loading...
11
11 Cited Publications
Cat. No.: HY-101068
CAS No.: 54857-86-2
Purity:  99.59%
Synonyms: RMI14514; MDL14514
Research Areas:  

Cancer

TOFA (RMI14514;MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA ).
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-103192
CAS No.: 40297-09-4
Purity:  99.82%
Synonyms: RMI12330A
MDL12330A (RMI12330A) is an adenylyl cyclases inhibitor. MDL12330A can inhibit KV channels, increases insulin secretion and Ca 2+ levels. MDL12330A accentuates contractions in uterine rings and inhibits cardiac functions. MDL12330A can be used for the research of endocrinology, metabolic and cardiovascular disease .
loading...
    loading...
Cat. No.: HY-124325
CAS No.: 622795-76-0
Purity:  ≥98.0%
Research Areas:  

Cancer

PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 μM. PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics .
loading...
    loading...
Cat. No.: HY-B0744D
CAS No.: 69955-42-6
Synonyms: L-DFMO monohydrochloride; ; L-RMI71782 monohydrochloride; L-α-difluoromethylornithine monohydrochloride
Target:  

Parasite

Research Areas:  

Cancer

L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min -1 .
loading...
    loading...
Cat. No.: HY-101656
CAS No.: 56290-94-9
Purity:  99.66%
Synonyms: RMI81968
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Medroxalol (RMI81968) is an orally active adrenergic receptor antagonist, blocks α- and β-adrenergic receptors. Medroxalol shows antihypertensive and vasodilating effects .
loading...
    loading...
Cat. No.: HY-B0744BR
CAS No.: 96020-91-6
Synonyms: DFMO hydrochloride hydrate (Standard); MDL-71782 hydrochloride hydrate (Standard); RMI-71782 hydrochloride hydrate (Standard); α-difluoromethylornithine hydrochloride hydrate (Standard)
Research Areas:  

Cancer

Eflornithine (hydrochloride hydrate) (Standard) is the analytical standard of Eflornithine (hydrochloride hydrate). This product is intended for research and analytical applications. Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .
loading...
    loading...
Cat. No.: HY-P11224
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

RMI-L4 is an efficient cyclic peptide inhibitor that can specifically disrupt the interaction between FANCM and RMI proteins with an IC50 of 54 nM. RMI-L4 engages the FANCM-binding pocket of RMI1/2 with nanomolar affinity (KD = 2.5 nM). RMI-L4 cannot penetrate the cell membrane and can be used to study the FANCM-RMI pathway targeting cancer with alternate lengthening of telomeres (ALT) .
loading...
    loading...
Cat. No.: HY-B0744C
CAS No.: 66640-93-5
Synonyms: L-DFMO; L-RMI71782; L-α-difluoromethylornithine
Target:  

Parasite

Research Areas:  

Cancer

L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min -1 .
loading...
    loading...
Cat. No.: HY-114692
CAS No.: 27511-99-5
Synonyms: EX 12-095; RMI 16238
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Eterobarb (EX 12-095), a barbiturate derivative, is an anticonvulsant agent .
loading...
    loading...
Cat. No.: HY-101220
CAS No.: 24140-98-5
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

RMI-61140 is an orally active neuroleptics. RMI-61140 decreases spontaneous motility and muscle tone in mice. RMI-61140 increases barbit urate-induced sleep and causes eyelid ptosis. RMI-61140 can be used for schizophrenia research .
loading...
    loading...
Cat. No.: HY-100279
CAS No.: 38020-45-0
Target:  

Antibiotic

Research Areas:  

Infection Cancer

RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone.
loading...
    loading...
Cat. No.: HY-RS12014
Research Areas:  

Others

RMI1 Human Pre-designed siRNA Set A contains three designed siRNAs for RMI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS12015
Research Areas:  

Others

RMI2 Human Pre-designed siRNA Set A contains three designed siRNAs for RMI2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS18496
Research Areas:  

Others

Rmi2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rmi2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS20335
Research Areas:  

Others

Rmi1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rmi1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS26843
Research Areas:  

Others

Rmi1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Rmi1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-101656A
CAS No.: 70161-10-3
Synonyms: RMI81968 hydrochloride
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Medroxalol hydrochloride is an orally active adrenergic receptor antagonist, blocks α- and β-adrenergic receptors. Medroxalol hydrochloride shows antihypertensive and vasodilating effects .
loading...
    loading...