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Cat. No.: HY-114692

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Eterobarb

(Synonyms: EX 12-095; RMI 16238)

Eterobarb (EX 12-095), a barbiturate derivative, is an anticonvulsant agent.

For research use only. We do not sell to patients.

CAS No.: 27511-99-5
Formula: C₁₆H₂₀N₂O₅
Molecular Weight:320.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Eterobarb Chemical Structure

CAS No.: 27511-99-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Eterobarb (EX 12-095), a barbiturate derivative, is an anticonvulsant agent^[1].

In Vivo

Eterobarb (25 mg/kg, i.p.) increases the threshold for the clonic seizure in mice^[1]

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Mice^[1]
Dosage:

25 mg/kg
Administration:

Intraperitoneal injection (i.p.)
Result:

Increased the threshold for the clonic seizure by 1.75.degree.

Chemical Information

CAS No. 27511-99-5
Molecular Weight 320.34
Formula C₁₆H₂₀N₂O₅
SMILES

O=C(N(C1=O)COC)N(C(C1(C2=CC=CC=C2)CC)=O)COC
Synonyms

EX 12-095; RMI 16238
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. R H Mattson, et al. Eterobarb therapy in epilepsy. Neurology. 1976 Nov;26(11):1014-7. [Content Brief]

[2]. R M Julien, et al. Effectiveness of N,N'-dimethoxymethylphenobarbital (eterobarbital) on febrile seizures. Proc West Pharmacol Soc. 1977;20:73-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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