1 Result for "

RTI-7470-44

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RTI-7470-44" in MCE Product Catalog:

Cat. No.: HY-147319
CAS No.: 825658-63-7
Purity:  99.85%
RTI-7470-44 is an orally active and blood-brain barrier-permeable antagonist of trace amine-associated receptor 1 (hTAAR1) with a Ki of 0.3 nM. RTI-7470-44 inhibits hTAAR1-mediated cAMP production and signal transduction (IC50 = 8.4 nM), and blocks hTAAR1-mediated GIRK current responses. RTI-7470-44 increases the spontaneous firing frequency of dopaminergic neurons and reduces collagen-induced platelet aggregation. RTI-7470-44 can be used in studies related to Parkinson's disease and gastric emptying .
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