4 Results for "

SCH42495

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "SCH42495" in MCE Product Catalog:

Cat. No.: HY-101682
CAS No.: 136511-43-8
Target:  

Neprilysin

Research Areas:  

Cardiovascular Disease

SCH 42495 is an orally active neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally active ethylester proagent of SCH 42354 .
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Cat. No.: HY-101682A
CAS No.: 145841-10-7
Target:  

Neprilysin

Research Areas:  

Cardiovascular Disease

SCH 42495 racemate is the racemate of SCH 42495. SCH 42495 is an orally active neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally active ethylester proagent of SCH 42354 .
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Cat. No.: HY-101682B
CAS No.: 156792-25-5
Target:  

Neprilysin

Research Areas:  

Cardiovascular Disease Others

(R)-SCH 42495 is the less active enantiomer of SCH 42495 . SCH 42495 is an orally active neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally active ethylester proagent of SCH 42354 .
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Cat. No.: HY-106975
CAS No.: 144505-58-8
Target:  

Neprilysin

Research Areas:  

Cardiovascular Disease

SCH-42354 is a potent, orally active neutral endopeptidase (NEP) inhibitor, is the pharmacologically active form of the proagent SCH-42495. SCH-42354 inhibits the hydrolysis of NEP to enhance the activity of atrial natriuretic peptide (ANP). SCH-42354 inhibits hydrolysis of leu-enkephalin and ANF with IC50 values of 8.3 nM and 10.0 nM, respectively. SCH-42354 has antihypertensive activity .
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