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(R)-SCH 42495 

Cat. No.: HY-101682B
Handling Instructions

(R)-SCH 42495 is the less active enantiomer of SCH 42495. SCH 42495 is an orally active neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally active ethylester prodrug of SCH 42354.

For research use only. We do not sell to patients.

(R)-SCH 42495 Chemical Structure

(R)-SCH 42495 Chemical Structure

CAS No. : 156792-25-5

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Description

(R)-SCH 42495 is the less active enantiomer of SCH 42495[1]. SCH 42495 is an orally active neutral metalloendopeptidase (NEP) inhibitor with antihypertensive effect. SCH 42495 is the orally active ethylester prodrug of SCH 42354[2].

In Vitro

NEP acts as a critical enzyme in the degradation. NEP cleaves atrial natriuretic factors (ANF) in vitro[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Inhibition of NEP in vivo has been shown to produce beneficial vasodilatory and natriuretic responses[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

411.58

Formula

C₂₀H₂₉NO₄S₂

CAS No.

156792-25-5

SMILES

CSCC[[email protected]@H](C(OCC)=O)NC([[email protected]](CSC(C)=O)CC1=CC=CC=C1C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

(R)-SCH 42495OthersInhibitorinhibitorinhibit

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(R)-SCH 42495
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