1 Result for "

SEN 177

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SEN 177" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-136780
CAS No.: 2117405-13-5
Purity:  98.76%
SEN177 is an orally effect glutamine cyclase (QC) inhibitor. The Ki of SEN177 for human glutamine cyclase (hQC) is 20 nM, and the IC50 is 13 nM. SEN177 interferes with the interaction between CD47 and SIRRPα, and has anti-tumor activity. SEN177 reduces aggregation and apoptosis caused by HTT mutation in Huntington model, and can be used in the study of neurodegenerative diseases .
loading...
    loading...