2 Results for "

SIRT6-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "SIRT6-IN-5" in MCE Product Catalog:

Cat. No.: HY-178990
Target:  

Sirtuin

Research Areas:  

Cancer

SIRT6-IN-5 (Compound 25) is a selective and safe SIRT6 inhibitor (IC50 = 18.91 µM). SIRT6-IN-5 can enhance the anti proliferative effect of chemotherapy agents. SIRT6-IN-5 can be used in the research of cancer, such as breast cancer .
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Cat. No.: HY-169846
CAS No.: 2488745-53-3
Target:  

Sirtuin

Research Areas:  

Metabolic Disease

CL5D is an activator of protein deacetylase SIRT6. CL5D can significantly enhance the deacetylation activity of SIRT6 and improve its catalytic efficiency. CL5D regulates SIRT6 activity by promoting conformational changes, especially dependent on the role of Arg-65 residue. CL5D can be used to study the activation mechanism of SIRT6 and its function in metabolism, DNA repair and aging .
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