2488745-53-3
Chemical Structure
CL5D
- CAS No.: 2488745-53-3
- Formula:C29H11Cl7N2O6
- Molecular Weight:731.58
InChIKey: UVJIIBHGVCKZJY-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2C(N(C3=CC=C(N(C(C4=C(Cl)C=C(Cl)C=C4Cl)=O)C(C5=C(Cl)C=C(Cl)C=C5Cl)=O)C(Cl)=C3)C(C2=C1)=O)=O)O
Biological Activity: CL5D is an activator of protein deacetylase SIRT6. CL5D can significantly enhance the deacetylation activity of SIRT6 and improve its catalytic efficiency. CL5D regulates SIRT6 activity by promoting conformational changes, especially dependent on the role of Arg-65 residue. CL5D can be used to study the activation mechanism of SIRT6 and its function in metabolism, DNA repair and aging[1].
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CL5D | CL5D is an activator of protein deacetylase SIRT6. CL5D can significantly enhance the deacetylation activity of SIRT6 and improve its catalytic efficiency. CL5D regulates SIRT6 activity by promoting conformational changes, especially dependent on the role of Arg-65 residue. CL5D can be used to study the activation mechanism of SIRT6 and its function in metabolism, DNA repair and aging. | |||||||||||||||||||||
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Keywords
