Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
SPN
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "SPN" in MCE Product Catalog:
4
4 Cited Publications
Target:
Research Areas:
SLF1081851 is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 plays a key role in development and immune system .
1
1 Cited Publications
Cat. No.: HY-162655
CAS No.: 2764877-61-2
Target:
Research Areas:
SLF80821178 is a potent and orally active inhibitor of Sphingosine-1-Phosphate Transporter (Spns2). SLF80821178 inhibits S1P release with an IC50 of 51 nM in HeLa cells and a T1/2 of 2.4 h in mouse .
1
1 Cited Publications
Cat. No.: HY-150254A
Purity: 99.91%
Target:
Research Areas:
SLB1122168 formic is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 formic inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC50 of 94 nM. SLB1122168 formic induces lymphopenia in circulating lymphocytes in mice and rats .
Cat. No.: HY-P0242
CAS No.: 86933-75-7
Cat. No.: HY-P0242A
CAS No.: 101536-55-4
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology
Target:
Research Areas:
Molindone ((±)-Molindone), an indole derivative, is a potent dopamine D2 and D5 receptor antagonist. Molindone ((±)-Molindone) can be used for the research of schizophrenia and severe mental illness .
Cat. No.: HY-150254
CAS No.: 2999629-17-1
Target:
Research Areas:
SLB1122168 is a Spinster Homolog 2 (Spns2) inhibitor. SLB1122168 inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release with an IC50 of 94 nM. SLB1122168 induces lymphopenia in circulating lymphocytes in mice and rats .
Cat. No.: HY-P10312
Target:
Research Areas:
Cat. No.: HY-RS13689
Target:
Research Areas:
SPN Human Pre-designed siRNA Set A contains three designed siRNAs for SPN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25080
Target:
Research Areas:
Spn Rat Pre-designed siRNA Set A contains three designed siRNAs for Spn gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156408
CAS No.: 3049214-20-9
Target:
Research Areas:
Spns2-IN-1 is a potent inhibitor of Spns2-dependent S1P transport (Spns2), with IC50 of 1.4±0.3 μM that plays an important role in immune response .
Cat. No.: HY-RS13690
Target:
Research Areas:
SPNS1 Human Pre-designed siRNA Set A contains three designed siRNAs for SPNS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13691
Target:
Research Areas:
SPNS2 Human Pre-designed siRNA Set A contains three designed siRNAs for SPNS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13692
Target:
Research Areas:
SPNS3 Human Pre-designed siRNA Set A contains three designed siRNAs for SPNS3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11006
Target:
Research Areas:
PPP1R9B Human Pre-designed siRNA Set A contains three designed siRNAs for PPP1R9B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-149004B
CAS No.: 2999629-35-3
Target:
Research Areas:
SLF1081851 (hydrochloride) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (hydrochloride) plays a key role in the development and immune system .
Cat. No.: HY-149004A
CAS No.: 2763730-98-7
Target:
Research Areas:
SLF1081851 (TFA) is a Spns2 inhibitor, inhibits S1P release (IC50=1.93 μM). SLF1081851 (TFA) plays a key role in development and immune system .
Cat. No.: HY-RS03666
Target:
Research Areas:
DEAF1 Human Pre-designed siRNA Set A contains three designed siRNAs for DEAF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-162655A
CAS No.: 2764877-62-3
Target:
Research Areas:
SLF80821178 hydrochloride is an orally active inhibitor for sphingosine-1-phosphate transporter (Spns2), that inhibits the sphingosine-1-phosphate (S1P) release in HeLa with an IC50 of 51 nM. SLF80821178 hydrochloride reduces the circulating lymphocyte without affecting plasma S1P levels in mice .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
