7416-34-4
7416-34-4
Chemical Structure
Molindone
Synonym(s): (±)-Molindone; SPN-810M
- CAS No.: 7416-34-4
- Formula:C16H24N2O2
- Molecular Weight:276.37
IUPAC Name: 3-ethyl-2-methyl-5-(morpholinomethyl)-1,5,6,7-tetrahydro-4H-indol-4-one
InChIKey: KLPWJLBORRMFGK-UHFFFAOYSA-N
SMILES: CCC1=C(C)NC(CCC2CN3CCOCC3)=C1C2=O
Biological Activity: Molindone ((±)-Molindone), an indole derivative, is a potent dopamine D2 and D5 receptor antagonist. Molindone ((±)-Molindone) can be used for the research of schizophrenia and severe mental illness[1][2].
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Molindone | Molindone ((±)-Molindone), an indole derivative, is a potent dopamine D2 and D5 receptor antagonist. Molindone ((±)-Molindone) can be used for the research of schizophrenia and severe mental illness. | |||||||||||||||||||||
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Molindone-d8 | 99.2% | Molindone-d8 is the deuterium labeled Molindone. Molindone hydrochloride (EN-1733A) is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses. | ||||||||||||||||||||
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References
- [1]. Krishna G, et al. In vitro and in vivo genotoxicity assessment of the dopamine receptor antagonist molindone hydrochloride. Environ Mol Mutagen. 2016;57(4):288-298. [Content Brief]
- [2]. Bagnall A, et al. Molindone for schizophrenia and severe mental illness. Cochrane Database Syst Rev. 2007;(1):CD002083. Published 2007 Jan 24. [Content Brief]
