2 Results for "

Sparfosic acid

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Sparfosic acid" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-112732
CAS No.: 51321-79-0
Target:  

Apoptosis

Research Areas:  

Metabolic Disease Cancer

Sparfosic acid, a DNA antimetabolite agent, is a potent inhibitor of aspartate transcarbamoyl transferase, the enzyme catalyzing the second step of de novo pyrimidine biosynthesis. Sparfosic acid synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines .
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6
6 Cited Publications
Cat. No.: HY-112732B
CAS No.: 70962-66-2
Purity:  ≥98.0%
Target:  

Apoptosis

Research Areas:  

Metabolic Disease Cancer

Sparfosic acid trisodium is a DNA antimetabolite agent and a potent inhibitor of aspartate transcarbamoyl transferase. Aspartate transcarbamoyl transferase catalyzes the second step of de novo pyrimidine biosynthesis. Sparfosic acid trisodium synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines .
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