3 Results for "

Sulindac sulfone

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Sulindac sulfone" in MCE Product Catalog:

Cat. No.: HY-B1787
CAS No.: 59973-80-7
Research Areas:  

Cancer

Sulindac sulfone is an orally active metabolite of Sulindac (HY-B0008). Sulindac sulfone activates PPARγ and drives transcriptional induction of SSAT by binding to the PPRE-2 element. Sulindac sulfone induces Apoptosis. Sulindac sulfone negatively regulates the function of VDAC1/2 to inhibit the mTORC1 pathway, reduces Cyclin D1 levels, and induces G1 cell cycle arrest in colon cancer cells. Sulindac sulfone exerts colon cancer preventive effects through a COX-independent mechanism. Sulindac sulfone can be used in research related to colon cancer .
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Cat. No.: HY-W742805
CAS No.: 2519512-94-6
Sulindac Sulfone-d6 is the deuterium labeled Sulindac sulfone (HY-B1787). Sulindac sulfone is an mTORC1 pathway inhibitor and a metabolite of Sulindac. Sulindac sulfone inhibits colon cancer cell growth and induces cell cycle arrest. Sulindac sulfone is used in cancer research .
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Cat. No.: HY-B1787S
CAS No.: 250608-67-4
Sulindac sulfone-d3 is deuterium labeled Sulindac sulfone.
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