1 Result for "

TRPM7-IN-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "TRPM7-IN-1" in MCE Product Catalog:

Cat. No.: HY-168608
CAS No.: 1909225-07-5
Research Areas:  

Cancer

TRPM7-IN-1 (compound SUD), a benzoylurea derivative, is an effective TRPM7 inhibitor. TRPM7-IN-1 induces cell cycle arrest and apoptosis, decreases the migration of MCF-7 and BGC-823 cells. TRPM7-IN-1 decreases vimentin expression and increases E-cadherin expression. TRPM7-IN-1 potentially reduces the TRPM7-like current and decreases TRPM7 expression through the PI3K/Akt signaling pathway. TRPM7-IN-1 is a potential agent to suppress the metastasis of breast and gastric cancer by inhibiting TRPM7 expression and function .
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