2 Results for "

TSLPR-IL-7Rα

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "TSLPR-IL-7Rα" in MCE Product Catalog:

Cat. No.: HY-P992447

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

QX008N is a humanized IgG1 monoclonal antibody and also a TSLP inhibitor with a KD value of 0.0175 nM. QX008N blocks TSLP-induced signaling pathways by inhibiting the interaction of TSLP-TSLPR-IL-7Rα. QX008N reduces eosinophil and IgE levels, improves pulmonary function, blocks TSLP-induced inflammation, and enhances the inhibitory effect on inflammatory mediators when administered in combination with anti-IL-4R antibodies. QX008N is applicable to relevant research on asthma .
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Cat. No.: HY-206870
CAS No.: 3104965-33-2
Research Areas:  

Inflammation/Immunology

BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP-mediated ternary complex formation, blocks TSLPR-IL7Rα co-localization, binds and stabilizes TSLPR, and inhibits phosphorylated STAT3/6. BP79 suppresses immune cell infiltration, secretion of IL-13, IL-4. BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis .
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