1 Result for "

Tubulin polymerization-IN-85

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Tubulin polymerization-IN-85" in MCE Product Catalog:

Cat. No.: HY-180190
Research Areas:  

Cancer

Tubulin polymerization-IN-85 (Compound C21) is a tubulin polymerization inhibitor (IC50 = 1.59 μM) targeting the colchicine binding site. Tubulin polymerization-IN-85 can cause cancer cells G2/M phase arrest and induce apoptosis. Tubulin polymerization-IN-85 downregulates the expression of Bcl-2, Bcl-xl, Mcl-1, Cyclin B1, cdc25, cdc2 protein and upregulates P53, P21, Bad and Bax levels. Tubulin polymerization-IN-85 can be used for the research of cancer, such as cervical cancer .
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