1 Result for "

WYE354

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "WYE354" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-12034
CAS No.: 1062169-56-5
Purity:  98.04%
Target:  

mTOR Autophagy Apoptosis

Research Areas:  

Cancer

WYE-354 is an ATP-competitive mTOR inhibitor with an IC50 of 5 nM. WYE-354 also inhibits PI3Kα and PI3Kγ with IC50s of 1.89 μM and 7.37 μM, respectively. WYE-354 inhibits both mTORC1 and mTORC2. WYE-354 induces autophagy activation in vitro .
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