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Results for "

ZEB1

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Natural
Products

1

Isotope-Labeled Compounds

3

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0153
    Naringin
    20+ Cited Publications

    Naringoside

    		 Cytochrome P450 Autophagy Mitophagy Endogenous Metabolite Inflammation/Immunology Cancer
    Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 (Zeb1) [1] .
    Naringin
  • HY-W011338
    Benzyl butyl phthalate
    1 Publications Verification

    		 Environmental Pollutants Aryl Hydrocarbon Receptor Cancer
    Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) [1] .
    Benzyl butyl phthalate
  • HY-RS16025
    ZEB1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ZEB1 Human Pre-designed siRNA Set A contains three designed siRNAs for ZEB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ZEB1 Human Pre-designed siRNA Set A
    ZEB1 Human Pre-designed siRNA Set A
  • HY-W011338S
    Benzyl butyl phthalate-d4

    		Aryl Hydrocarbon Receptor Cancer
    Benzyl butyl phthalate-d4 is the deuterium labeled Benzyl butyl phthalate [1]. Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) .
    Benzyl butyl phthalate-d4
  • HY-131445
    RJW100
    1 Publications Verification

    		 MicroRNA Endocrinology Cancer
    RJW100 is a potent liver receptor homolog 1 (LRH-1, NR5A2) and steroidogenic factor-1 (SF-1, NR5A1) agonist with pEC50s of 6.6 and 7.5, respectively [1]. RJW100 also causes strong activation of the miR-200c (miRNA-200c, microRNA-200c) promoter .
    RJW100
  • HY-RS16881
    Zeb1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Zeb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Zeb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Zeb1 Mouse Pre-designed siRNA Set A
    Zeb1 Mouse Pre-designed siRNA Set A
  • HY-N0153R
    Naringin (Standard)
    20+ Cited Publications

    Naringoside (Standard)

    		 Endogenous Metabolite Cytochrome P450 Mitophagy Autophagy Reference Standards Inflammation/Immunology Cancer
    Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. Naringin also inhibits proliferation and invasion and induces apoptosis in human osteosarcoma cells by inhibiting zinc finger E-box binding homeobox 1 (Zeb1) [1] .
    Naringin (Standard)
  • HY-RS23323
    Zeb1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Zeb1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Zeb1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Zeb1 Rat Pre-designed siRNA Set A
    Zeb1 Rat Pre-designed siRNA Set A
  • HY-W011338R
    Benzyl butyl phthalate (Standard)

    		Reference Standards Aryl Hydrocarbon Receptor Cancer
    Benzyl butyl phthalate (Standard) is the analytical standard of Benzyl butyl phthalate. This product is intended for research and analytical applications. Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs) [1] .
    Benzyl butyl phthalate (Standard)
  • HY-183629
    ZNF281-IN-1

    		Zinc Finger Protein Apoptosis Cardiovascular Disease Cancer
    ZNF281-IN-1 is a ZNF281 inhibitor. ZNF281-IN-1 disrupts the binding of transcriptionally active DNA-bound ZNF281 to the promoters of target genes including TRIM35 and ZEB1. ZNF281-IN-1 inhibits tumor cell proliferation, stabilizes P53 and upregulates PUMA to induce apoptosis, while triggering cellular senescence. ZNF281-IN-1 completely prevents Doxorubicin (HY-15142A)-induced cardiotoxicity (AIC), and enhances rather than impairs the antitumor efficacy of Doxorubicin. ZNF281-IN-1 completely blocks the distant metastasis of melanoma to the lungs. ZNF281-IN-1 can be used in the research of cardiotoxicity, lung cancer and metastatic melanoma [1].
    ZNF281-IN-1
  • HY-W072962
    WX2-43

    		Histone Methyltransferase PAK Bcl-2 Family KLF Cancer
    WX2-43 is a PRMT5-KLF4 inhibitor (Kd of 11.0 nM). WX2-43 binds to the region between amino acids L400-M500 on PRMT5. WX2-43 efficiently intercepts the interaction between KLF4 and PRMT5, and blocks KLF4 methylation. WX2-43 decreases p21 levels and increases Bax levels. WX2-43 suppresses triple negative breast tumor progression. WX2-43 can be used in the research of triple-negative breast cancer and colorectal cancer [1] .
    WX2-43

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