85-68-7
85-68-7
Chemical Structure
Benzyl butyl phthalate
- CAS. Nr.: 85-68-7
- Formula:C19H20O4
- Molecular Weight:312.36
IUPAC Name: benzyl butyl phthalate
InChIKey: IRIAEXORFWYRCZ-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C1C(OCC2=CC=CC=C2)=O)OCCCC
Biological Activity: Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs)[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Benzyl butyl phthalate | Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs). | |||||||||||||||||||||
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Benzyl butyl phthalate (Standard) | ≥98% | Benzyl butyl phthalate (Standard) is the analytical standard of Benzyl butyl phthalate. This product is intended for research and analytical applications. Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs). | ||||||||||||||||||||
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Benzyl butyl phthalate-d4 | 99.35% | Benzyl butyl phthalate-d4 is the deuterium labeled Benzyl butyl phthalate. Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs). | ||||||||||||||||||||
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Dibenzyl phthalate | Dibenzyl phthalate, a diaryl phthalate, is extensively used as a plasticizer to modify the properties of the synthetic resin substrates, resulting in the improvement of flexibility and durability of the end products. Dibenzyl phthalate is an endocrine-disrupting compound, and activates estrogen and androgen receptors. | |||||||||||||||||||||
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Dibenzyl Phthalate-d4 | Dibenzyl Phthalate-d4 is the deuterium labeled Dibenzyl Phthalate. | |||||||||||||||||||||
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Monooctyl phthalate-d4 | 96.36% | Monooctyl phthalate-d4 (Mono-n-octyl phthalate-d4) is a deuterium labeled Monooctyl phthalate (HY-133671). Monooctyl phthalate (Mono-n-octyl phthalate) exhibits antimycobacterial activity with a MIC of 20 μg/mL. | ||||||||||||||||||||
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Mono-n-Pentyl Phthalate-3,4,5,6-d4 | Mono-n-Pentyl Phthalate-3,4,5,6-d4 is the deuterium labeled Mono-n-Pentyl Phthalate. | |||||||||||||||||||||
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Benzyl salicylate (Standard) | ≥98% | Benzyl salicylate (Standard) (NSC 6647 (Standard)) is the analytical standard of Benzyl salicylate (HY-B1556). This product is intended for research and analytical applications. Benzyl salicylate (NSC 6647)?is a salicylic acid benzyl ester. It can be used as a fragrance additive or UV light absorber. | ||||||||||||||||||||
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Dipropyl phthalate (Standard) | ≥98% | Dipropyl phthalate (Standard) is the analytical standard of Dipropyl phthalate (HY-B1944). This product is intended for research and analytical applications. Dipropyl phthalate is an immunomodulator. Dipropyl phthalate alters the activities of acid phosphatase, phenoloxidase and superoxide dismutase, increases the activity of β-glucuronidase in a dose-dependent manner, and elevates the mRNA level of hemocyanin in shrimp. Dipropyl phthalate activates the FoxO signaling pathway, interferes with cell proliferation and apoptosis, downregulates chondrocyte-related genes, and induces craniofacial cartilage developmental malformations in zebrafish embryos. Dipropyl phthalate can be used in studies related to Aeromonas veronii infection and micrognathia syndrome. | ||||||||||||||||||||
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Dipropyl phthalate-d4 | 99.02% | Dipropyl phthalate-d4 (NSC 15314-d4) is the deuterated-labeled Dipropyl phthalate (HY-B1944). Dipropyl phthalate is an immunomodulator. Dipropyl phthalate alters the activities of acid phosphatase, phenoloxidase and superoxide dismutase, increases the activity of β-glucuronidase in a dose-dependent manner, and elevates the mRNA level of hemocyanin in shrimp. Dipropyl phthalate activates the FoxO signaling pathway, interferes with cell proliferation and apoptosis, downregulates chondrocyte-related genes, and induces craniofacial cartilage developmental malformations in zebrafish embryos. Dipropyl phthalate can be used in studies related to Aeromonas veronii infection and micrognathia syndrome. | ||||||||||||||||||||
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Monobutyl phthalate | 99.72% | Monobutyl phthalate is an orally active metabolite of Di-n-butyl phthalate (HY-Y0304) and an embryotoxic agent. Monobutyl phthalate regulates mesodermal lineage gene expression, inhibits uterine decidualization, reduces fetal testosterone levels without directly binding to the androgen receptor, and induces teratogenic effects during organogenesis. Monobutyl phthalate induces testicular oxidative stress and sperm abnormalities. Monobutyl phthalate can be used in studies of developmental toxicity and male reproductive toxicity. | ||||||||||||||||||||
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Monobutyl phthalate-d4 | 98.43% | Monobutyl phthalate-d4 is the deuterium labeled Monobutyl phthalate. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant. | ||||||||||||||||||||
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Butyl isobutyl phthalate | 99.31% | Butyl isobutyl phthalate is isolated from the rhizoid of Laminaria japonica. Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor with an IC50 value of 38 μM. Butyl isobutyl phthalate shows a hypoglycemic effect and has the potential for diabetes treatment. | ||||||||||||||||||||
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Dihexyl phthalate-3,4,5,6-d4 | 98.20% | Dihexyl phthalate-3,4,5,6-d4 is the deuterated-labeled Dihexyl phthalate (HY-W011215). Dihexyl phthalate is an orally active phthalate ester (PAEs) widely used as a plasticizer, and it acts as an environmental endocrine disruptor. Dihexyl phthalate exhibits endocrine-disrupting and reproductive toxic properties, induces oxidative stress and inflammation, and ultimately causes apoptosis and damage to reproductive organs such as the testes. Dihexyl phthalate can be used in studies related to developmental toxicity, embryonic lethality, teratogenicity, and abnormal development of the male reproductive system. | ||||||||||||||||||||
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Monobenzyl phthalate | 99.88% | Monobenzyl phthalate is a phthalate metabolite (aromatic alkyl chain monophthalate) with oral activity, which acts as a male reproductive development inhibitor and antiandrogen in rat fetuses. | ||||||||||||||||||||
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Monobenzyl phthalate-d4 | 99.40% | Monobenzyl phthalate-d4 is the deuterium labeled Monobenzyl phthalate. Monobenzyl phthalate (2-((Benzyloxy)carbonyl)benzoic acid) is the urinary metabolite exposuring to phthalates, such as, diethylhexyl phthalate (DEHP). | ||||||||||||||||||||
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Dipentyl phthalate (Standard) | ≥98% | Dipentyl phthalate (Standard) is the analytical standard of Dipentyl phthalate. This product is intended for research and analytical applications. Dipentyl phthalate is an endocrine-disrupting phthalate plasticizer. Dipentyl phthalate increases AMPK phosphorylation and decreases AKT1 phosphorylation and SIRT1 levels. Dipentyl phthalate reduces adrenocorticotropic hormone levels. Dipentyl phthalate is a testicular toxicant. | ||||||||||||||||||||
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Dipentyl phthalate-3,4,5,6-d4 | 99.3% | Dipentyl phthalate-3,4,5,6-d4 is the deuterium labeled Dipentyl phthalate-3,4,5,6. | ||||||||||||||||||||
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Monohexyl phthalate | 98.81% | Monohexyl phthalate is a competitive inhibitor towards UGT1A9, with an IC50 of 12.46 μM and a Ki of 7.47 μM. | ||||||||||||||||||||
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2-((Heptyloxy)carbonyl)benzoic acid-d4 | 2-((Heptyloxy)carbonyl)benzoic acid-d4 is the deuterium labeled 2-((Heptyloxy)carbonyl)benzoic acid (HY-W705420). | |||||||||||||||||||||
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Dibutyl phthalate | 99.85% | Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects. | ||||||||||||||||||||
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Dibutyl phthalate-3,4,5,6-d4 | 99.54% | Dibutyl phthalate-3,4,5,6-d4 is the deuterium labeled Dibutyl phthalate. Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects. | ||||||||||||||||||||
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References
- [1]. Sun G, et al. Developmental toxicity and cardiac effects of butyl benzyl phthalate in zebrafish embryos. Aquat Toxicol. 2017;192:165-170. [Content Brief]
- [2]. Cui S, et al. Benzyl butyl phthalate (BBP) triggers the migration and invasion of hemangioma cells via upregulation of Zeb1. Toxicol In Vitro. 2019;60:323-329. [Content Brief]
- [3]. Wang YC, et al. Benzyl butyl phthalate promotes breast cancer stem cell expansion via SPHK1/S1P/S1PR3 signaling. Oncotarget. 2016;7(20):29563-29576. [Content Brief]
