Dihexyl phthalate-3,4,5,6-d4
Based on 1 Customer Validation
Dihexyl phthalate-3,4,5,6-d4 is the deuterium labeled Dihexyl phthalate-3,4,5,6. Dihexyl phthalate (HY-W011215) is one of the commonly used phthalate esters in various plastics and consumer products. Dihexyl phthalate is classified as a priority pollutant and an endocrine disruptor. Dihexyl phthalate can induce reactive oxygen species (ROS) accumulation, promote inflammation, and lead to significant increases in apoptosis and inflammation-related gene expression levels. Dihexyl phthalate can cause testicular atrophy and is a reproductive toxicant.
For research use only. We do not sell to patients.
- Purity: 98.20%
- CAS No.: 1015854-55-3
- Formula: C20H26D4O4
- Molecular Weight:338.47
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1015854-55-3
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Unlabeled Cas 84-75-3
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Appearance Liquid
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Molecular Weight 338.47
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Formula C20H26D4O4
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Color Colorless to light yellow
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SMILES
CCCCCCOC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(OCCCCCC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (295.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Kim YH, et al. Enhanced degradation and toxicity reduction of dihexyl phthalate by Fusarium oxysporum f. sp. pisi cutinase. J Appl Microbiol. 2007 Jan;102(1):221-8. [Content Brief]
[2]. Song D, et al. Combining metabolomics with bioanalysis methods to investigate the potential toxicity of dihexyl phthalate[J]. Environmental toxicology, 2021, 36(2): 213-222. [Content Brief]
[3]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9545 mL | 14.7724 mL | 29.5447 mL | 73.8618 mL |
| 5 mM | 0.5909 mL | 2.9545 mL | 5.9089 mL | 14.7724 mL | |
| 10 mM | 0.2954 mL | 1.4772 mL | 2.9545 mL | 7.3862 mL | |
| 15 mM | 0.1970 mL | 0.9848 mL | 1.9696 mL | 4.9241 mL | |
| 20 mM | 0.1477 mL | 0.7386 mL | 1.4772 mL | 3.6931 mL | |
| 25 mM | 0.1182 mL | 0.5909 mL | 1.1818 mL | 2.9545 mL | |
| 30 mM | 0.0985 mL | 0.4924 mL | 0.9848 mL | 2.4621 mL | |
| 40 mM | 0.0739 mL | 0.3693 mL | 0.7386 mL | 1.8465 mL | |
| 50 mM | 0.0591 mL | 0.2954 mL | 0.5909 mL | 1.4772 mL | |
| 60 mM | 0.0492 mL | 0.2462 mL | 0.4924 mL | 1.2310 mL | |
| 80 mM | 0.0369 mL | 0.1847 mL | 0.3693 mL | 0.9233 mL | |
| 100 mM | 0.0295 mL | 0.1477 mL | 0.2954 mL | 0.7386 mL |
Dihexyl phthalate-3,4,5,6-d4 Related Classifications
HY-W011215S Related Classifications
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