84-75-3
84-75-3
Chemical Structure
Dihexyl phthalate
- CAS 番号: 84-75-3
- Formula:C20H30O4
- Molecular Weight:334.46
IUPAC Name: dihexyl phthalate
InChIKey: KCXZNSGUUQJJTR-UHFFFAOYSA-N
SMILES: O=C(OCCCCCC)C1=CC=CC=C1C(OCCCCCC)=O
Biological Activity: Dihexyl phthalate is an orally active phthalate ester (PAEs) widely used as a plasticizer, and it acts as an environmental endocrine disruptor. Dihexyl phthalate exhibits endocrine-disrupting and reproductive toxic properties, induces oxidative stress and inflammation, and ultimately causes apoptosis and damage to reproductive organs such as the testes. Dihexyl phthalate can be used in studies related to developmental toxicity, embryonic lethality, teratogenicity, and abnormal development of the male reproductive system[1][2][3][4][5].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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Dihexyl phthalate | 98.73% | Dihexyl phthalate is an orally active phthalate ester (PAEs) widely used as a plasticizer, and it acts as an environmental endocrine disruptor. Dihexyl phthalate exhibits endocrine-disrupting and reproductive toxic properties, induces oxidative stress and inflammation, and ultimately causes apoptosis and damage to reproductive organs such as the testes. Dihexyl phthalate can be used in studies related to developmental toxicity, embryonic lethality, teratogenicity, and abnormal development of the male reproductive system. | ||||||||||||||||||||
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Dihexyl phthalate (Standard) | ≥98% | Dihexyl phthalate (Standard) is the analytical standard of Dihexyl phthalate (HY-W011215). This product is intended for research and analytical applications. Dihexyl phthalate is an orally active phthalate ester (PAEs) widely used as a plasticizer, and it acts as an environmental endocrine disruptor. Dihexyl phthalate exhibits endocrine-disrupting and reproductive toxic properties, induces oxidative stress and inflammation, and ultimately causes apoptosis and damage to reproductive organs such as the testes. Dihexyl phthalate can be used in studies related to developmental toxicity, embryonic lethality, teratogenicity, and abnormal development of the male reproductive system. | ||||||||||||||||||||
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Dihexyl phthalate-3,4,5,6-d4 | 98.20% | Dihexyl phthalate-3,4,5,6-d4 is the deuterated-labeled Dihexyl phthalate (HY-W011215). Dihexyl phthalate is an orally active phthalate ester (PAEs) widely used as a plasticizer, and it acts as an environmental endocrine disruptor. Dihexyl phthalate exhibits endocrine-disrupting and reproductive toxic properties, induces oxidative stress and inflammation, and ultimately causes apoptosis and damage to reproductive organs such as the testes. Dihexyl phthalate can be used in studies related to developmental toxicity, embryonic lethality, teratogenicity, and abnormal development of the male reproductive system. | ||||||||||||||||||||
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Diisohexyl phthalate | 98.77% | Diisohexyl phthalate is a type of dialkyl phthalate plasticizer. Diisohexyl phthalate may pose potential interference to the chromatographic analysis of polyvinyl chloride (PVC) samples. | ||||||||||||||||||||
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Dipropyl phthalate | 98.19% | Dipropyl phthalate is an immunomodulator. Dipropyl phthalate alters the activities of acid phosphatase, phenoloxidase and superoxide dismutase, increases the activity of β-glucuronidase in a dose-dependent manner, and elevates the mRNA level of hemocyanin in shrimp. Dipropyl phthalate activates the FoxO signaling pathway, interferes with cell proliferation and apoptosis, downregulates chondrocyte-related genes, and induces craniofacial cartilage developmental malformations in zebrafish embryos. Dipropyl phthalate can be used in studies related to Aeromonas veronii infection and micrognathia syndrome. | ||||||||||||||||||||
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Didecyl phthalate | Didecyl phthalate is the primary plasticizer for vinyl resins and is also compatible with polystyrene and cellulose. | |||||||||||||||||||||
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Diheptyl phthalate | 98.64% | Diheptyl phthalate is a class of phthalates consisting of two heptyl (C7) chains attached to a phthalic acid backbone. This compound is commonly used as a plasticizer in various polymer materials such as PVC to increase flexibility and durability. It can also be used as a lubricant, solvent or additive in various industrial applications such as coatings, adhesives and sealants. However, Diheptyl phthalate has been identified as an environmental pollutant and health hazard due to its potential for endocrine disruption and toxicity. | ||||||||||||||||||||
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Dioctyl phthalate | 99.40% | Dioctyl phthalate (DNOP) is a plasticizer. Dioctyl phthalate increases the activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the liver, as well as the levels of creatinine and urea in the kidney. Exposure to Dioctyl phthalate disrupts the homeostasis of the intestinal microbial community, increases the abundance of pathogenic bacteria, and reduces the abundance of beneficial bacteria such as Lactobacillus. Dioctyl phthalate induces significant and dose-dependent inflammatory responses in the liver, spleen and kidney of mice. | ||||||||||||||||||||
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Dipentyl phthalate (Standard) | ≥98% | Dipentyl phthalate (Standard) is the analytical standard of Dipentyl phthalate. This product is intended for research and analytical applications. Dipentyl phthalate is an endocrine-disrupting phthalate plasticizer. Dipentyl phthalate increases AMPK phosphorylation and decreases AKT1 phosphorylation and SIRT1 levels. Dipentyl phthalate reduces adrenocorticotropic hormone levels. Dipentyl phthalate is a testicular toxicant. | ||||||||||||||||||||
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Monohexyl phthalate | 98.81% | Monohexyl phthalate is a competitive inhibitor towards UGT1A9, with an IC50 of 12.46 μM and a Ki of 7.47 μM. | ||||||||||||||||||||
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Diisohexyl phthalate (DIP) (Standard) | ≥98% | Diisohexyl phthalate (DIP) (Standard) is the analytical standard of Diisohexyl phthalate (DIP). This product is intended for research and analytical applications. | ||||||||||||||||||||
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Butyl 2-ethylhexyl phthalate | Butyl 2-ethylhexyl phthalate is isolated from Parthenium hysterophorus flower. | |||||||||||||||||||||
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Dibutyl phthalate (Standard) | ≥98% | Dibutyl phthalate (Standard) is the analytical standard of Dibutyl phthalate. This product is intended for research and analytical applications. Dibutyl phthalate is a commonly used plasticizer commonly found in some food packaging materials, personal care products, and the coating of oral medications. May cause toxicity and adverse neurobehavioral effects. | ||||||||||||||||||||
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References
- [1]. Wang W, et al. Metabolic and neurodevelopmental effects of the environmental endocrine disruptor di-2-ethylhexyl phthalate: a review. Environmental Chemistry Letters. 2025 Feb;23(1):321-35.
- [2]. Saillenfait AM, et al. Differential developmental toxicities of di-n-hexyl phthalate and dicyclohexyl phthalate administered orally to rats. Journal of applied toxicology : JAT. 2009 Aug;29(6):510-21.
- [3]. Sung HH, et al. Effects and toxicity of phthalate esters to hemocytes of giant freshwater prawn, Macrobrachium rosenbergii. Aquatic toxicology (Amsterdam, Netherlands). 2003 Jun 19;64(1):25-37.
- [4]. Wang H, et al. Phthalate Esters Released from Plastics Promote Biofilm Formation and Chlorine Resistance. Environmental science & technology. 2022 Jan 18;56(2):1081-1090.
- [5]. Ganning AE, et al. Phthalate esters and their effect on the liver. Hepatology (Baltimore, Md.). 1984;4(3):541-7. [Content Brief]
