1. Immunology/Inflammation
  2. Aryl Hydrocarbon Receptor
  3. Benzyl butyl phthalate

Benzyl butyl phthalate 

Cat. No.: HY-W011338
Handling Instructions

Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs).

For research use only. We do not sell to patients.

Benzyl butyl phthalate Chemical Structure

Benzyl butyl phthalate Chemical Structure

CAS No. : 85-68-7

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
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5 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to stimulate SPHK1/S1P/S1PR3 signaling and enhances formation of metastasis-initiating breast cancer stem cells (BCSCs)[1][2][3].

In Vitro

Benzyl butyl phthalate (BBP) is commonly added during the manufacturing of plastics to increase flexibility and elasticity[1].
Benzyl butyl phthalate induces histone modifications in S1PR3 in side population (SP) cells, but not in non-SP cells[3].

Molecular Weight

312.36

Formula

C₁₉H₂₀O₄

CAS No.

85-68-7

SMILES

O=C(C1=CC=CC=C1C(OCC2=CC=CC=C2)=O)OCCCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (320.14 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2014 mL 16.0072 mL 32.0143 mL
5 mM 0.6403 mL 3.2014 mL 6.4029 mL
10 mM 0.3201 mL 1.6007 mL 3.2014 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

Benzyl butyl phthalateAryl Hydrocarbon ReceptorAhRtoxicphthalateZeb1HemangiomabreastcancercellsstemInhibitorinhibitorinhibit

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Benzyl butyl phthalate
Cat. No.:
HY-W011338
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