2 Results for "

ZINC000019796155

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ZINC000019796155" in MCE Product Catalog:

13
13 Cited Publications
Cat. No.: HY-14539
CAS No.: 5786-21-0
Purity:  99.84%
Synonyms: HF 1854; ZINC000019796155
Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively . Clozapine is also a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM) .
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Cat. No.: HY-14539S5
CAS No.: 1233341-42-8
Synonyms: HF 1854-d11; ZINC000019796155-d11
Clozapine-d11 (HF 1854-d11) is the deuterium labeled Clozapine (HY-14539). Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively Clozapine is also a potent and selective agonist at the muscarinic M4 receptor (EC50 = 11 nM).
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