29 Results for "

alkaloid derivative

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "alkaloid derivative" in MCE Product Catalog:

8
8 Publications Verification
Cat. No.: HY-13295
CAS No.: 42971-09-5
Purity:  99.57%
Synonyms: Ethyl apovincaminate
Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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2
2 Cited Publications
Cat. No.: HY-W014971
CAS No.: 343-94-2
Tryptamine hydrochloride belongs to the class of indole alkaloids and is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds. It can also occur naturally in certain plants and animals, including fungi and mammals. Due to the psychoactive properties of Tryptamine hydrochloride and its derivatives, its use and possession are controlled substances in many countries.
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1
1 Cited Publications
Cat. No.: HY-118581
CAS No.: 38989-38-7
Purity:  98.30%
Target:  

Topoisomerase

Research Areas:  

Cancer

Coralyne chloride is a protoberberine alkaloid with potent anti-cancer activities. Coralyne chloride acts as a potent topoisomerase I poison and induces Top I mediated DNA cleavage . Coralyne chloride can be used for preparing?coralyne derivatives?as DNA binding fluorescent probes .
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1
1 Cited Publications
Cat. No.: HY-20897A
CAS No.: 25197-99-3
5-Bromo-L-tryptophan is a substrate of PLP-dependent enzyme AetE, as well as an indole alkaloid and Amino acid derivative. 5-Bromo-L-tryptophan can be isolated from Semenospongia sp. 5-Bromo-L-tryptophan can be converted into 5-bromoindole (HY-30236) via AetE-mediated catalysis. 5-Bromo-L-tryptophan is applicable to colon cancer research .
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1
1 Cited Publications
Cat. No.: HY-A0220
CAS No.: 24815-24-5
Synonyms: Reserpinine
Rescinnamine is a derivative of the indole alkaloid reserpine. Rescinnamine shows sedative effects. Rescinnamine can be used for hypertension research .
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Cat. No.: HY-139570
CAS No.: 2248127-53-7
Synonyms: PM14
Target:  

Bacterial

Ecubectedin (PM14) is a derivative. Ecteinascidins is a family of tetrahydroisoquinoline alkaloids with wide range of antitumor and antimicrobial activities .
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Cat. No.: HY-W001963
CAS No.: 634-97-9
Pyrrole-2-carboxylic acid is a natural alkaloid from the marine bacterium Pelomonas puraquae sp. Nov. Pyrrole-2-carboxylic acid is a biological form of pyrrole that is often encountered in natural compounds. Pyrrole-2-carboxylic acid serves as a precursor for various pyrrole derivatives like clorobiocin, coumermycin A1, pyoluteorin, leupyrrins, and undecylprodigiosin in biosynthetic processes .
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Cat. No.: HY-W178327
CAS No.: 4921-49-7
Target:  

Adenosine Receptor

Research Areas:  

Cancer

8-Chloro caffeine binds to adenosine receptors (Ki = 30 µM). 8-Chloro caffeine potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine .
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Cat. No.: HY-N4012
CAS No.: 5548-10-7
Synonyms: 3-Indoleglyoxamide
Indole-3-glyoxylamide (Compound 4) is a type of indole alkaloid. Indole-3-glyoxylamide shows no significant cytotoxic activity against Hela, Ishikawa, and MGC-803 cells .
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Cat. No.: HY-13295R
CAS No.: 42971-09-5
Synonyms: Ethyl apovincaminate (Standard)
Vinpocetine (Standard) is the analytical standard of Vinpocetine. This product is intended for research and analytical applications. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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Cat. No.: HY-N12726
CAS No.: 2977255-36-8
Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities .
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Cat. No.: HY-118425
CAS No.: 524-46-9
Synonyms: O-Methylcorledine
(+)-Adlumine (O-Methylcorledine) is an alkaloid derivative found in Corydalis ledebouriana .
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Cat. No.: HY-W033010
CAS No.: 135-97-7
Synonyms: β-Tropine
Pseudotropine (β-Tropine), a derivative of Tropane, is a plant alkaloid .
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Cat. No.: HY-W665464
CAS No.: 130144-34-2
Research Areas:  

Cancer

(Rac)-7-Ethyl-10-hydroxycamptothecin is the derivative of (±)-10-Hydroxycamptothecin (HY-N0275). (±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity .
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Cat. No.: HY-172530
Research Areas:  

Neurological Disease

Heptanoyl-coenzyme A (Heptanoyl-CoA) tetrasodium is a derivative of CoA. Heptanoyl-coenzyme A tetrasodium is an inhibitor of butyryl-CoA acetate-CoA transferase (BUT) and inhibits butyric acid synthesis. Heptanoyl-coenzyme A tetrasodium blocks the improvements in motor function induced by the isoquinoline alkaloid Berberine (HY-N0716) .
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Cat. No.: HY-106072
CAS No.: 67699-40-5
Synonyms: LY 104208
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Vinzolidine is a semisynthetic derivative of the catharanthus alkaloid. Vinzolidine exerts its cytotoxic effect on tumor cells by interfering with microtubulin polymerization, thereby inhibiting cell division. Vinzolidine can be utilized in research to investigate synergistic effects when combined with other chemotherapeutic agents or biologic therapies, as well as to study cancer cells' tolerance or resistance to these treatments, and to explore approaches to overcome such obstacles .
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Cat. No.: HY-13295S
CAS No.: 2734920-39-7
Vinpocetine-d5 is the deuterium labeled Vinpocetine. Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na+ channels. The IC50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB-dependent inflammatory responses by directly targeting IκB kinase complex (IKK), and has been widely used for the treatment of cerebrovascular disorders .
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Cat. No.: HY-105608
CAS No.: 131-28-2
Synonyms: Narcein
Narceine (Narcein), a quinolone derivative, is an opium alkaloid with anti-diabetic property .
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Cat. No.: HY-172846
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

6-Methoxy-N,N-diethylpentylone hydrochloride is an alkaloid derivative and can be used for the research of neurological disease.
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Cat. No.: HY-175065
Synonyms: N,N-Dimethyl hexanophenone hydrochloride; N-Dimethyl hexedrone hydrochloride
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

α-Dimethylaminohexanophenone (N,N-dimethyl Hexanophenone, N-dimethyl Hexedrone) hydrochloride is an alkaloid derivative and can be used for the research of neurological disease.
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