25197-99-3
25197-99-3
Chemical Structure
5-Bromo-L-tryptophan
- CAS No.: 25197-99-3
- Formula:C11H11BrN2O2
- Molecular Weight:283.13
IUPAC Name: (S)-2-amino-3-(5-bromo-1H-indol-3-yl)propanoic acid
InChIKey: KZDNJQUJBMDHJW-VIFPVBQESA-N
SMILES: N[C@@H](CC1=CNC2=CC=C(Br)C=C12)C(O)=O
Biological Activity: 5-Bromo-L-tryptophan is a substrate of PLP-dependent enzyme AetE, as well as an indole alkaloid and Amino acid derivative. 5-Bromo-L-tryptophan can be isolated from Semenospongia sp. 5-Bromo-L-tryptophan can be converted into 5-bromoindole (HY-30236) via AetE-mediated catalysis. 5-Bromo-L-tryptophan is applicable to colon cancer research[1][2][3].
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5-Bromo-L-tryptophan | 99.61% | 5-Bromo-L-tryptophan is a substrate of PLP-dependent enzyme AetE, as well as an indole alkaloid and Amino acid derivative. 5-Bromo-L-tryptophan can be isolated from Semenospongia sp. 5-Bromo-L-tryptophan can be converted into 5-bromoindole (HY-30236) via AetE-mediated catalysis. 5-Bromo-L-tryptophan is applicable to colon cancer research. | ||||||||||||||||||||
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5-Bromo-L-tryptophan (Standard) | ≥98% | 5-Bromo-L-tryptophan (Standard) is the analytical standard of 5-Bromo-L-tryptophan (HY-20897A). This product is intended for research and analytical applications. 5-Bromo-L-tryptophan is an α-amino acid derivative that can be found in Semenospongia sp.. 5-Bromo-L-tryptophan can be used to synthesize 5-bromoindole (HY-30236). | ||||||||||||||||||||
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References
- [1]. Adak S, et al. From Tryptophan to Toxin: Nature's Convergent Biosynthetic Strategy to Aetokthonotoxin. Journal of the American Chemical Society. 2022 Feb 23;144(7):2861-2866. [Content Brief]
- [2]. Tasdemir D, et al. Cytotoxic bromoindole derivatives and terpenes from the Philippine marine sponge Smenospongia sp. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2002;57(9-10):914-22. [Content Brief]
- [3]. Adak S, et al. Metagenomic Identification of Brominated Indole Biosynthetic Machinery from Cyanobacteria. Journal of natural products. 2025 Jul 25;88(7):1734-1742. [Content Brief]
