24 Results for "

anticonvulsive

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "anticonvulsive" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-B0358
CAS No.: 52468-60-7
Flunarizine is a potent dual Na +/Ca 2+ channel (T-type) blocker. Flunarizine is a D2 dopamine receptor antagonist. Flunarizine shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects .
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6
6 Publications Verification
Cat. No.: HY-B0358A
CAS No.: 30484-77-6
Flunarizine dihydrochloride is a potent dual Na +/Ca 2+ channel (T-type) blocker. Flunarizine dihydrochloride is a D2 dopamine receptor antagonist. Flunarizine dihydrochloride shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects .
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1
1 Cited Publications
Cat. No.: HY-P1932A
Cortistatin-14 (TFA), a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 (TFA) shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties .
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Cat. No.: HY-B1184A
CAS No.: 70989-04-7
Synonyms: (+)-Mephenytoin
Target:  

Cytochrome P450

Research Areas:  

Neurological Disease

(S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism .
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Cat. No.: HY-101335
CAS No.: 147782-19-2
Purity:  ≥99.0%
Target:  

mGluR

Research Areas:  

Neurological Disease

DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 μM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1R/5R=389/630 μM) and III receptors (IC50: mGlu4R/6R/7R/8R= 22.5/39.6/40.1/32 μM). DCG-IV has anticonvulsive and neuroprotective effects .
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Cat. No.: HY-B1671
CAS No.: 500-64-1
(+)-Kavain, a main kavalactone that can be extracted from Piper methysticum, has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na + and Ca 2+ channels . (+)-Kavain is shown to bind at the α4β2δ GABAA receptor and potentiate GABA efficacy . (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied .
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Cat. No.: HY-108587
CAS No.: 325457-99-6
Purity:  99.85%
Target:  

Potassium Channel

Research Areas:  

Neurological Disease

ICA 110381 is an orally active Kv7.2/Kv7.3 (KCNQ2/3) potassium channel activator with anticonvulsive properties. ICA 110381 is a KCNQ2/Q3 activator (EC50=0.38 μM) as well as KCNQ1 antagonist (IC50=15 μM) .
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Cat. No.: HY-B1184AR
CAS No.: 70989-04-7
Synonyms: (+)-Mephenytoin (Standard)
Research Areas:  

Neurological Disease

(S)-Mephenytoin (Standard) is the analytical standard of (S)-Mephenytoin. This product is intended for research and analytical applications. (S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsive agent. (S)-Mephenytoin is a substrate of the cytochrome P450 (CYP) isoform CYP2C19. (S)-Mephenytoin can be used for the analysis of cytochrome P450 metabolism .
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Cat. No.: HY-105791
CAS No.: 2898-13-7
Purity:  99.53%
Target:  

GABA Receptor

Research Areas:  

Inflammation/Immunology

Sulazepam, a benzodiazepine, is a selective ovarian cancer G protein-coupled receptor (OGR1) agonist. Sulazepam has anticonvulsive action and has the potential for airway hyperresponsiveness (AHR) research .
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Cat. No.: HY-107514
CAS No.: 120667-15-4
Purity:  99.76%
Target:  

mGluR

Research Areas:  

Neurological Disease

(RS)-PPG is a potent and selective agonist for group III mGluRs. The EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively. Anticonvulsive and neuroprotective activity .
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Cat. No.: HY-B0358AR
CAS No.: 30484-77-6
Flunarizine (dihydrochloride) (Standard) is the analytical standard of Flunarizine (dihydrochloride). This product is intended for research and analytical applications. Flunarizine dihydrochloride is a potent dual Na +/Ca 2+ channel (T-type) blocker. Flunarizine dihydrochloride is a D2 dopamine receptor antagonist. Flunarizine dihydrochloride shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects .
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Cat. No.: HY-105791S
Sulazepam-d5 is a deuterium labeled Sulazepam (HY-105791). Sulazepam is a selective ovarian cancer G protein-coupled receptor (OGR1) agonist .
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Cat. No.: HY-Z8176
CAS No.: 693765-11-6
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

(Z)-Flunarizine is the (Z)-isomer of Flunarizine (HY-B0358). Flunarizine is a potent dual Na +/Ca 2+ channel (T-type) blocker. Flunarizine is a D2 dopamine receptor antagonist. Flunarizine shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects .
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Cat. No.: HY-B0358AS
Flunarizine-d8 dihydrochloride is deuterated labeled Flunarizine dihydrochloride (HY-B0358A). Flunarizine dihydrochloride is a potent dual Na +/Ca 2+ channel (T-type) blocker. Flunarizine dihydrochloride is a D2 dopamine receptor antagonist. Flunarizine dihydrochloride shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects .
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Cat. No.: HY-B1585A
CAS No.: 125-85-9
Synonyms: Parpanil hydrochloride
Target:  

mAChR

Research Areas:  

Neurological Disease

Caramiphen hydrochloride is a muscarinic antagonist. Caramiphen hydrochloride shows anticonvulsive properties. Caramiphen hydrochloride offers partial protection against Soman-induced seizures and neuropathology .
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Cat. No.: HY-118696
CAS No.: 1426208-69-6
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

MGAT2-IN-5 (Compound 17b) is a selective inhibitor for mouse GABA transit protection subsidity 2 (mGAT2) with an IC50 of 45 μM. MGAT2-IN-5 exhibits anticonvulsive efficacy in audiogenic seizure (AGS) susceptible frings mouse model with an ED50 of 20.4 mg/kg .
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Cat. No.: HY-19435
CAS No.: 220445-20-5
Target:  

iGluR Cytochrome P450

Research Areas:  

Neurological Disease

GYKI-47261 is a competitive, orally active, and selective AMPA receptor antagonist with an IC50 of 2.5 μM. GYKI-47261 has broad spectrum anticonvulsive activity and neuroprotective effects. GYKI-47261 is also a potent inducer of CYP2E1 .
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Cat. No.: HY-19435A
CAS No.: 1217049-32-5
Target:  

iGluR Cytochrome P450

Research Areas:  

Neurological Disease

GYKI-47261 dihydrochloride is a competitive, orally active, and selective AMPA receptor antagonist with an IC50 of 2.5 μM. GYKI-47261 has broad spectrum anticonvulsive activity and neuroprotective effects. GYKI-47261 dihydrochloride is also a potent inducer of CYP2E1 .
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Cat. No.: HY-B0358R
CAS No.: 52468-60-7
Flunarizine (Standard) is the analytical standard of Flunarizine. This product is intended for research and analytical applications. Flunarizine is a potent dual Na +/Ca 2+ channel (T-type) blocker. Flunarizine is a D2 dopamine receptor antagonist. Flunarizine shows anticonvulsive and antimigraine activity, and peripheral vasodilator effects .
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Cat. No.: HY-N11015
CAS No.: 949172-12-7
Withaphysalin R (compound 5) is a Withanolide that can be isolated from the Solanaceae. Withanolide is a steroid ester with an ergosterol skeleton, and some of these compounds have some significant activities, including cytotoxic and immunosuppressive, antitumor, anti-inflammatory, anticonvulsive, and antioxidant .
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