![[Des-Tyr1]-gamma-Endorphin](https://file.medchemexpress.com/product_pic/hy-p10498.gif "Click to View [Des-Tyr1]-gamma-Endorphin Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
antidepressant efficacy
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "antidepressant efficacy" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: EMD 68843; SB659746A
Target:
Research Areas:
Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active serotonin reuptake inhibitor (SSRI) and partial 5-HT1A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders .
1
1 Cited Publications
Synonyms: AZD6765 dihydrochloride; ARL 15896AR
Target:
Research Areas:
Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .
1
1 Cited Publications
Cat. No.: HY-P3641A
Target:
Research Areas:
Target:
Research Areas:
XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms .
Cat. No.: HY-108235
CAS No.: 153322-05-5
Synonyms: AZD6765
Target:
Research Areas:
Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .
Cat. No.: HY-P3641
CAS No.: 374675-18-0
Target:
Research Areas:
Cat. No.: HY-175285
CAS No.: 780703-57-3
Target:
Research Areas:
5-HT2AR-IN-1 (Compound Ie) is an orally active 5-hydroxytryptamine 2A receptor (5-HT2AR) inhibitor with antidepressant efficacy. 5-HT2AR-IN-1 reduces 5-HT2AR expression and SERT protein levels. 5-HT2AR-IN-1 is promising for research of central nervous system (CNS), such as depression and addiction-related disorders .
Target:
Research Areas:
Amitriptylinoxide (Equilibrin) is an analogue and metabolite of amitriptyline with similar antidepressant efficacy .
Cat. No.: HY-W744788
Synonyms: Equilibrin-d6
Cat. No.: HY-14262S1
Synonyms: EMD 68843-d8; SB659746A-d8
Synonyms: (Rac)-AZD6765
Target:
Research Areas:
(Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .
Cat. No.: HY-108235BR
CAS No.: 61890-25-3
Synonyms: (Rac)-AZD6765 (Standard)
Target:
Research Areas:
(Rac)-Lanicemine (Standard) is the analytical standard of (Rac)-Lanicemine. This product is intended for research and analytical applications. (Rac)-Lanicemine ((Rac)-AZD6765) is the racemate of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects .
Cat. No.: HY-169140
CAS No.: 114298-18-9
Synonyms: WY-47846
Target:
Research Areas:
Zalospirone (WY-47846) is a novel cyclic imide with 5-HT1A partial agonist activity. Zalospirone shows antidepressant efficacy .
Cat. No.: HY-12390S
CAS No.: 1185083-78-6
Cat. No.: HY-117606
CAS No.: 1377615-76-3
Target:
Research Areas:
LY3027788, a diester analog of LY3020371 which is an mGlu2/3 receptor antagonist, is a potent and orally active prodrug of LY3020371. LY3027788 has antidepressant efficacy .
Cat. No.: HY-117606A
CAS No.: 1377615-55-8
Target:
Research Areas:
LY3027788 hydrochloride, a diester analog of LY3020371 which is an mGlu2/3 receptor antagonist, is a potent and orally active prodrug of LY3020371. LY3027788 hydrochloride has antidepressant efficacy .
Cat. No.: HY-P10498
CAS No.: 67810-56-4
Target:
Research Areas:
Cat. No.: HY-14262R
CAS No.: 163521-12-8
Synonyms: EMD 68843 (Standard); SB659746A (Standard)
Research Areas:
Vilazodone (Standard) is the analytical standard of Vilazodone. This product is intended for research and analytical applications. Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active serotonin reuptake inhibitor (SSRI) and partial 5-HT1A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders .
Cat. No.: HY-W775346
CAS No.: 23050-54-6
Synonyms: Δ8-THC acetate; Delta8-tetrahydrocannabinol
Target:
Research Areas:
Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive phytocannabinoid, that binds to cannabinoid receptor 1 (CB1 receptor), and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory activities. Delta8-THC acetate exhibits probably neuroprotective efficacy and can be used in anti-anxiety and antidepressant research .
Cat. No.: HY-160921
CAS No.: 769901-96-4
Synonyms: SL65.0155 free base
Target:
Research Areas:
Capeserod (SL65.0155 free base) is an agonist for serotonin receptor (5-HT receptor), with a Ki of 0.6 nM for 5-HT4 receptor. Capeserod enhances expression of phopshorilated cAMP-response element binding protein (p-CREB), vascular endothelium growth factor (VEGF), brain-derived neurotrophic factor (BDNF) and B cell lymphoma-2 (Bcl-2) proteins in hippocampus, and exhibits antidepressant-like efficacy in Wistar rats models .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
