5-HT2AR-IN-1
5-HT2AR-IN-1 (Compound Ie) is an orally active 5-hydroxytryptamine 2A receptor (5-HT2AR) inhibitor with antidepressant efficacy. 5-HT2AR-IN-1 reduces 5-HT2AR expression and SERT protein levels. 5-HT2AR-IN-1 is promising for research of central nervous system (CNS), such as depression and addiction-related disorders.
For research use only. We do not sell to patients.
- CAS No.: 780703-57-3
- Formula: C19H21NO3
- Molecular Weight:311.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT2 Receptor |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| EL4 | IC50 |
20.67 μM
Compound: I4
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Cytotoxicity against mouse EL4 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
Cytotoxicity against mouse EL4 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay
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[PMID: 37154394] |
Chemical Information
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CAS No. 780703-57-3
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Molecular Weight 311.37
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Formula C19H21NO3
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SMILES
COC1=CC2=C(CC3NCCC4=CC(OC)=C(C2=C43)OC)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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