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bFGF (119-126)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "bFGF (119-126)" in MCE Product Catalog:

6
bFGF (119-126)
bFGF (119-126)
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6 Cited Publications
Cat. No.: HY-P5321
CAS No.: 152051-61-1
Target:  

FGFR

Research Areas:  

Cancer

bFGF (119-126) is a ligand of bFGF. The complex formed by bFGF (119-126) and bFGF can bind to FGFR1, while inhibiting the bFGF-FGFR1 interaction, FGFR1 phosphorylation and downstream signaling pathways. Therefore, bFGF (119-126) induces cell apoptosis and inhibits cell proliferation, migration, angiogenesis and metastasis. When conjugated with a carrier, bFGF (119-126) enhances cellular uptake via FGFR-mediated endocytosis and serves as an effective FGFR-targeted ligand. When used in combination with ultrasound and Doxorubicin (HY-15142A), bFGF (119-126) significantly enhances the inhibitory effect on tumors. bFGF (119-126) is applicable to research related to lung cancer, breast cancer, glioblastoma and ovarian cancer .
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