2 Results for "

c-Met-IN-28

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "c-Met-IN-28" in MCE Product Catalog:

Cat. No.: HY-183672
Target:  

c-Met/HGFR

Research Areas:  

Cancer

c-Met-IN-28 is a type III allosteric inhibitor of c-MET, with pKi values of 7.4 (WT) and 7.1 (D1228V), and IC50 values of 37 nM (WT) and 72 nM (D1228V) against human c-MET. c-Met-IN-28 can be used for research on c-MET-driven cancers .
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Cat. No.: HY-162868
Target:  

c-Met/HGFR HDAC Apoptosis

Research Areas:  

Cancer

c-Met/HDAC-IN-4 is a dual inhibitor of c-Met/HDAC. The IC50 value of c-Met/HDAC-IN-4 for c-Met is 28.92 nM. c-Met/HDAC-IN-4 can induce G0/G1 phase cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells, and it inhibits the proliferation and invasion of breast cancer cell lines .
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