428 Results for "

carboxylated

" in MedChemExpress (MCE) Product Catalog:
Products (428)

428 Results for "carboxylated" in MCE Product Catalog:

28
28 Publications Verification
Cat. No.: HY-W018746
CAS No.: 139-33-3
Synonyms: Ethylenediaminetetraacetic acid disodium
EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.
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6
6 Cited Publications
Cat. No.: HY-101884
CAS No.: 576-19-2
Purity:  99.91%
Synonyms: (+)-Biocytin
Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the -amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays .
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3
3 Cited Publications
Cat. No.: HY-W037893
CAS No.: 122323-88-0
Synonyms: Methyl piperazine-2-carboxylate dihydrochloride; METTL3 activator-1
Target:  

METTL3 HIV

Research Areas:  

Infection Neurological Disease

CHMA1004 (Methyl piperazine-2-carboxylate; METTL3 activator-1) dihydrochloride is a METTL3/METTL14/WTAP methyltransferase complex activator. CHMA1004 dihydrochloride exhibits neuroprotective and anxiolytic potential by enhancing m 6A methylation modification of RNA. CHMA1004 dihydrochloride promotes HIV replication in an infection context. CHMA1004 dihydrochloride can be used in studies related to anxiety disorders and HIV-1 infection .
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3
3 Cited Publications
Cat. No.: HY-17042
CAS No.: 83881-51-0
Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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3
3 Cited Publications
Cat. No.: HY-17042A
CAS No.: 83881-52-1
Synonyms: P071
Cetirizine dihydrochloride, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine dihydrochloride marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response .
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2
2 Cited Publications
Cat. No.: HY-126271
CAS No.: 709-85-3
Purity:  99.79%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

PYCR1-IN-1 (compound 4) is a pyrroline-5-carboxylate reductase 1 (PYCR1) inhibitor with an IC50 of 8.8 µM. PYCR1-IN-1 has anticancer effects .
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2
2 Cited Publications
Cat. No.: HY-P2831
CAS No.: 9016-18-6
Synonyms: CESs
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Esterase, pig liver (CESs), namely carboxylate hydrolases, are widely distributed in nature, commonly found in mammalian liver, and often used in biochemical research. Esterase catalyzes the hydrolysis of a variety of endogenous and exogenous substrates, including esters, thioesters, carbamates, and amides, hydrolyzing carboxylic acid esters to the corresponding alcohols and carboxylic acids .
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1
1 Cited Publications
Cat. No.: HY-W002128
CAS No.: 16732-70-0
Ethyl 5-bromo-1H-indole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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1
1 Cited Publications
Cat. No.: HY-Y0949
CAS No.: 611-13-2
Synonyms: Methyl furan-2-carboxylate
Methyl 2-furoate (Methyl furan-2-carboxylate) can be used to synthesize cis-fused 5-oxofuro[2,3-b]furans. Methyl 2-furoate is also used in the preparation of sesquiterpene lactones .
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1
1 Cited Publications
Cat. No.: HY-15992
CAS No.: 894783-71-2
Target:  

VEGFR

Research Areas:  

Cancer

BIBF 1202 is the carboxylate metabolite of Nintedanib (HY-50904) which inhibits VEGFR2 kinase with an IC50 of 62 nM.
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Cat. No.: HY-40146
CAS No.: 398489-26-4
Synonyms: N-Boc-3-azetidinone
tert-Butyl 3-oxoazetidine-1-carboxylate is a synthetic intermediate. tert-Butyl 3-oxoazetidine-1-carboxylate can be used in compound research and development targeting cancer and tuberculosis .
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Cat. No.: HY-W454945S
CAS No.: 1126621-86-0
Synonyms: N-Boc-piperazine-d8
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8 is the deuterium labeled tert-Butyl piperazine-1-carboxylate .
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Cat. No.: HY-138354A
CAS No.: 72978-16-6
Purity:  98.87%
Target:  

Drug Intermediate

Research Areas:  

Infection

Pyrroline-5-carboxylate sodium is a key intermediate in proline anabolism and catabolism. Pyrroline-5-carboxylate sodium plays important roles in plant defense against pathogen invasion, as well as in redox regulation, nucleotide synthesis and other processes in animal cells .
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Cat. No.: HY-33615
CAS No.: 100202-39-9
Research Areas:  

Cancer

Methyl azetidine-3-carboxylate hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl azetidine-3-carboxylate hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs<
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Cat. No.: HY-W052289
CAS No.: 868656-97-7
Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with anti-tumor activity. Methyl 6-bromo-1H-indole-3-carboxylate exhibits growth inhibitory effects against Staphylococcus epidermidis. Methyl 6-bromo-1H-indole-3-carboxylate can be used in research related to Staphylococcus epidermidis infection and cancer .
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Cat. No.: HY-40151
CAS No.: 610791-05-4
Research Areas:  

Cancer

Methyl 1-Boc-azetidine-3-carboxylate is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Methyl 1-Boc-azetidine-3-carboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1
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Cat. No.: HY-79635
CAS No.: 942-24-5
Methyl indole-3-carboxylate is a Sorangium metabolite. Methyl indole-3-carboxylate shows weak activity against Gram-positive Nocardia sp with a MIC of 33.3 μg/mL .
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Cat. No.: HY-W012071
CAS No.: 16652-71-4
Research Areas:  

Others

(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is an intermediate in the synthesis of L-proline derivative peptides. (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is a key raw material for the synthesis of apoptosis inhibitor protein (IAP) antagonists and SMAC mimic tripeptide fragments (Boc-MeAla-Tle-Pro-OH). (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride can be used to synthesize divalent quinazoline IAP antagonists .
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Cat. No.: HY-137494
CAS No.: 74214-62-3
Purity:  99.75%
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Ethyl β-carboline-3-carboxylate (fl-CCE) is a ligand and short-acting antagonist of benzodiazepine receptors. Ethyl β-carboline-3-carboxylate did not affect cerebellar cGMP levels when used alone, but when taken together with Diazepam, it significantly inhibited the cGMP levels that were upregulated by Diazepam .
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Cat. No.: HY-40143
CAS No.: 142253-54-1
Target:  

PROTAC Linkers

Research Areas:  

Cancer

tert-Butyl 3-cyanoazetidine-1-carboxylate is a PROTAC linker that can be used in the synthesis of PROTACs.
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