Methyl 6-bromo-1H-indole-3-carboxylate
Based on 1 Customer Validation
Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with anti-tumor activity. Methyl 6-bromo-1H-indole-3-carboxylate exhibits growth inhibitory effects against Staphylococcus epidermidis. Methyl 6-bromo-1H-indole-3-carboxylate can be used in research related to Staphylococcus epidermidis infection and cancer.
For research use only. We do not sell to patients.
- Purity : 98.22%
- CAS No.: 868656-97-7
- Formula: C10H8BrNO2
- Molecular Weight:254.08
-
Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All Endogenous Metabolite Isoforms
More
Biological Activity
Description
In Vitro
Methyl 6-bromo-1H-indole-3-carboxylate (Compound 10) inhibits the growth of Staphylococcus epidermidis (ATCC 12228) with an MIC of 6.25 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 868656-97-7
-
Appearance Solid
-
Molecular Weight 254.08
-
Formula C10H8BrNO2
-
Color Off-white to light yellow
-
SMILES
O=C(C1=CNC2=C1C=CC(Br)=C2)OC
-
Structure Classification
-
Initial Source
Thorectandra and Smenospongia
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (393.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (275 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
[1]. Segraves NL, et al. Investigation of brominated tryptophan alkaloids from two thorectidae sponges: Thorectandra and Smenospongia. J Nat Prod. 2005;68(10):1484-1488. [Content Brief]
[2]. Platsoucas CD, et al. Immune responses to human tumors: development of tumor vaccines. Anticancer Res. 2003 May-Jun;23(3A):1969-96. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9358 mL | 19.6788 mL | 39.3577 mL | 98.3942 mL |
| 5 mM | 0.7872 mL | 3.9358 mL | 7.8715 mL | 19.6788 mL | |
| 10 mM | 0.3936 mL | 1.9679 mL | 3.9358 mL | 9.8394 mL | |
| 15 mM | 0.2624 mL | 1.3119 mL | 2.6238 mL | 6.5596 mL | |
| 20 mM | 0.1968 mL | 0.9839 mL | 1.9679 mL | 4.9197 mL | |
| 25 mM | 0.1574 mL | 0.7872 mL | 1.5743 mL | 3.9358 mL | |
| 30 mM | 0.1312 mL | 0.6560 mL | 1.3119 mL | 3.2798 mL | |
| 40 mM | 0.0984 mL | 0.4920 mL | 0.9839 mL | 2.4599 mL | |
| 50 mM | 0.0787 mL | 0.3936 mL | 0.7872 mL | 1.9679 mL | |
| 60 mM | 0.0656 mL | 0.3280 mL | 0.6560 mL | 1.6399 mL | |
| 80 mM | 0.0492 mL | 0.2460 mL | 0.4920 mL | 1.2299 mL | |
| 100 mM | 0.0394 mL | 0.1968 mL | 0.3936 mL | 0.9839 mL |