Methyl 6-bromo-1H-indole-3-carboxylate

Name: Methyl 6-bromo-1H-indole-3-carboxylate
Brand: MedChemExpress
SKU: HY-W052289
Rating: 4.5 (0 reviews)

Cat. No.: HY-W052289 Purity: 98.22%: Data Sheet
COA

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Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with anti-tumor activity. Methyl 6-bromo-1H-indole-3-carboxylate exhibits growth inhibitory effects against Staphylococcus epidermidis. Methyl 6-bromo-1H-indole-3-carboxylate can be used in research related to Staphylococcus epidermidis infection and cancer.

For research use only. We do not sell to patients.

Methyl 6-bromo-1H-indole-3-carboxylate Chemical Structure

CAS No. : 868656-97-7

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Other Forms of Methyl 6-bromo-1H-indole-3-carboxylate:

Methyl 6-bromo-1H-indole-3-carboxylate (Standard) Get quote

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Description

In Vitro

Methyl 6-bromo-1H-indole-3-carboxylate (Compound 10) inhibits the growth of Staphylococcus epidermidis (ATCC 12228) with an MIC of 6.25 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

254.08

Formula

C₁₀H₈BrNO₂

CAS No.

868656-97-7

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=CNC2=C1C=CC(Br)=C2)OC

Structure Classification

Initial Source

Thorectandra and Smenospongia

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (393.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9358 mL	19.6788 mL	39.3577 mL
5 mM	0.7872 mL	3.9358 mL	7.8715 mL
10 mM	0.3936 mL	1.9679 mL	3.9358 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.81%

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Data Sheet (275 KB) SDS (393 KB)

COA (253 KB) HNMR (96 KB) RP-HPLC (124 KB)

Handling Instructions (2659 KB)

References

[1]. Segraves NL, et al. Investigation of brominated tryptophan alkaloids from two thorectidae sponges: Thorectandra and Smenospongia. J Nat Prod. 2005;68(10):1484-1488. [Content Brief]

[2]. Platsoucas CD, et al. Immune responses to human tumors: development of tumor vaccines. Anticancer Res. 2003 May-Jun;23(3A):1969-96. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.9358 mL	19.6788 mL	39.3577 mL	98.3942 mL
	5 mM	0.7872 mL	3.9358 mL	7.8715 mL	19.6788 mL
	10 mM	0.3936 mL	1.9679 mL	3.9358 mL	9.8394 mL
	15 mM	0.2624 mL	1.3119 mL	2.6238 mL	6.5596 mL
	20 mM	0.1968 mL	0.9839 mL	1.9679 mL	4.9197 mL
	25 mM	0.1574 mL	0.7872 mL	1.5743 mL	3.9358 mL
	30 mM	0.1312 mL	0.6560 mL	1.3119 mL	3.2798 mL
	40 mM	0.0984 mL	0.4920 mL	0.9839 mL	2.4599 mL
	50 mM	0.0787 mL	0.3936 mL	0.7872 mL	1.9679 mL
	60 mM	0.0656 mL	0.3280 mL	0.6560 mL	1.6399 mL
	80 mM	0.0492 mL	0.2460 mL	0.4920 mL	1.2299 mL
	100 mM	0.0394 mL	0.1968 mL	0.3936 mL	0.9839 mL