576-19-2
576-19-2
Chemical Structure
Biocytin
Synonym(s): (+)-Biocytin
- CAS No.: 576-19-2
- Formula:C16H28N4O4S
- Molecular Weight:372.48
IUPAC Name: N6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)-L-lysine
InChIKey: BAQMYDQNMFBZNA-MNXVOIDGSA-N
SMILES: N[C@@H](CCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)C(O)=O
Biological Activity: Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the -amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Biocytin | 99.91% | Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the -amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays. | ||||||||||||||||||||
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Biocytin (Standard) | ≥98% | Biocytin (Standard) is the analytical standard of Biocytin. This product is intended for research and analytical applications. Biocytin is a conjugate of D-biotin and L-lysine, where the carboxylate of D-biotin is coupled with the -amine of L-lysine via a secondary amide bond. Biocytin is a classical neuroanatomical tracer commonly used to map brain connectivity. Biocytin is used as a versatile marker in anterograde, retrograde and intracellular neuroanatomical investigations and in biotinidase assays. | ||||||||||||||||||||
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N-Biotinyl-6-aminohexanoic acid | 99.84% | N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform biotinylation. | ||||||||||||||||||||
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Biotin LC hydrazide | 99.78% | Biotin LC hydrazide is a long chain protein modification reagent, which can transform periodate-oxidized glycoproteins. | ||||||||||||||||||||
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5-(Biotinamido)pentylazide | 5-Biotinamidopentylazide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. 5-(Biotinamido)pentylazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Biocytin hydrazide | 99.24% | Biocytin hydrazide is a long-chain biotin-containing hydrazide, serving as a biotin-derived active coupling reagent, selective labeling agent and biotinylating reagent. Biocytin hydrazide targets aldehyde, carboxyl, amino and guanidino groups to biotinylate glycoconjugates, K99 lectin, peptides and proteins through its hydrazide moiety, and achieves nonradioactive detection of sialic acid- and galactose-containing glycoconjugates via the avidin–biotin system. | ||||||||||||||||||||
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L-Lysine-Biotin | L-Lysine-Biotin is an L-Lysine conjugated with biotin. Temporin L-lysine-biotin, generated by conjugating L-Lysine-Biotin with temporin L, can serve as a molecular anchor for displaying streptavidin on the surface of bacterial magnetosome (BMP) membranes. L-Lysine-Biotin can be used for tracking L-Lysine. | |||||||||||||||||||||
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5-(Biotinamido)pentylamine | 99.96% | 5-(Biotinamido)pentylamine is an amine donor substrate for transglutaminase. 5-(Biotinamido)pentylamine can be used as a biotin-labeled probe to specifically participate in the calcium-dependent reaction catalyzed by TG, bind to the γ-carboxamide group of the glutamine residue in the protein, introduce the biotin tag into the target protein, and form a biotinylated protein product. 5-(Biotinamido)pentylamine can be used for the labeling, separation, and detection of TG amine receptor protein substrates. | ||||||||||||||||||||
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Biotin-C4-amide-C5-NH2 | 95.0% | Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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N-Biotinyl-4-aminobutanoic acid | N-Biotinyl-4-aminobutanoic acid is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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N-Biotinyl-1,6-hexanediaMine | 99.57% | N-Biotinyl-1,6-hexanediaMine is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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6-N-Biotinylaminohexanol | 6-N-Biotinylaminohexanol is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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References
- [1]. Mishra A, et al. Improved neuronal tract tracing with stable biocytin-derived neuroimaging agents. ACS Chem Neurosci. 2010 Feb 17;1(2):129-38. [Content Brief]
- [2]. Roth G, et al. Morphology and axonal projection pattern of neurons in the telencephalon of the fire-bellied toad Bombina orientalis: an anterograde, retrograde, and intracellular biocytin labeling study. J Comp Neurol. 2004 Oct 4;478(1):35-61. [Content Brief]
