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EDTA disodium  (Synonyms: Ethylenediaminetetraacetic acid disodium)

Cat. No.: HY-W018746 Purity: 99.2%
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EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.

For research use only. We do not sell to patients.

CAS No. : 139-33-3

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Based on 25 publication(s) in Google Scholar

Other Forms of EDTA disodium:

EDTA disodium Related Antibodies

Top Publications Citing Use of Products

    EDTA disodium purchased from MedChemExpress. Usage Cited in: Nat Immunol. 2025 Oct;26(10):1660-1672.  [Abstract]

    Representative images of CHMP4–GFP puncta (arrowheads; left) and percentage of CHMP4 speckle+ (top right) or Annexin V+ (bottom right) cells in BMDMs incubated with PBS, 15 µM SK56, 2 mM EDTA or EDTA + SK56 at 2 h after the addition of 1 μg/ml LPS + 10 μM nigericin; scale bar, 50 µm; n = 5 repeats

    • Biological Activity

    • Purity & Documentation

    • Customer Review

    Description

    EDTA disodium salt, also known as ethylenediaminetetraacetic acid disodium, belongs to the chelating agent category, which is formed by chelating a central metal ion with four carboxylate groups and two amine groups. This compound, with its ability to bind and chelate metal ions such as calcium, magnesium and iron, is commonly used in a variety of applications, including industrial, medical and research settings. It is used as a preservative in food and beverage, as a stabilizer in medicine, as a chelating agent in water treatment, and as a reagent in biochemical and biomedical research. In addition, EDTA disodium salt has been studied for potential research effects such as improving heavy metal poisoning and cardiovascular disease.

    In Vitro

    EDTA disodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    EDTA disodium Related Antibodies
    Molecular Weight

    336.21

    Formula

    C10H14N2Na2O8
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=C(O)CN(CC(O)=O)CCN(CC(O[Na])=O)CC(O[Na])=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Store at room temperature 3 years

    In solvent -80°C 2 years
    -20°C 1 year
    Solvent & Solubility
    In Vitro: 

    H2O : 20 mg/mL (59.49 mM; ultrasonic and warming and heat to 60°C)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.9743 mL 14.8717 mL 29.7433 mL
    5 mM 0.5949 mL 2.9743 mL 5.9487 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.2%

    SDS (557 KB)

    COA (248 KB) HNMR (109 KB)

    Handling Instructions (2659 KB)

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 2.9743 mL 14.8717 mL 29.7433 mL 74.3583 mL
    5 mM 0.5949 mL 2.9743 mL 5.9487 mL 14.8717 mL
    10 mM 0.2974 mL 1.4872 mL 2.9743 mL 7.4358 mL
    15 mM 0.1983 mL 0.9914 mL 1.9829 mL 4.9572 mL
    20 mM 0.1487 mL 0.7436 mL 1.4872 mL 3.7179 mL
    25 mM 0.1190 mL 0.5949 mL 1.1897 mL 2.9743 mL
    30 mM 0.0991 mL 0.4957 mL 0.9914 mL 2.4786 mL
    40 mM 0.0744 mL 0.3718 mL 0.7436 mL 1.8590 mL
    50 mM 0.0595 mL 0.2974 mL 0.5949 mL 1.4872 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    EDTA disodium Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    EDTA disodium139-33-3Ethylenediaminetetraacetic acid disodiumBiochemical Assay ReagentsEnvironmental PollutantsEnvironmental Contaminantsbiochemical assayreagentInhibitorinhibitorinhibit

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