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chloroform extracts

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By Targets:	Amylases (1) Bacterial (1) Biochemical Assay Reagents (1) Cholinesterase (ChE) (1) Drug Derivative (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (2) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2732

6-Prenylapigenin 6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin	Others	Cancer
6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells .

HY-N10685

3,7,25-Trihydroxycucurbita-5,23-dien-19-al TCD	Drug Derivative	Others Cancer
3,7,25-Trihydroxycucurbita-5,23-dien-19-al (TCD) is a natural product, that can be isolated from the chloroform extract of the leaves of Momordica foetida .

HY-N12702

Volvalerenal E	Others	Others
Volvalerenal E is an active product that can be isolated from a chloroform extract of the roots of Valeriana officinalis var. latifolia. .

HY-N9294

2',4'-Dihydroxy-7-methoxy-8-prenylflavan	Biochemical Assay Reagents	Others
2',4'-Dihydroxy-7-methoxy-8-prenylflavan (compound 6) is a compound isolated from a chloroform-soluble extract of dried Morus alba fruits .

HY-N10791

Neobritannilactone B	Others	Infection
Neobritannilactone B, a sesquiterpene, can be isolated from the chloroform fraction of the I. britannica. Neobritannilactone B is cytotoxic. Other extracts of I. britannica are also Dihydrofolate reductase (DHFR) inhibitors, which inhibit Shigella dysenteriae type 1 .

HY-N15374

Hypercalin B	Bacterial	Infection
Hypercalin B is an antibacterial agent that can be isolated from the hexane and chloroform extracts of the plant Hypericum acmosepalum. Hypercalin B exhibits inhibitory activity against multidrug-resistant strains of Staphylococcus aureus, with a MIC range of 0.5-128 mg/L .

HY-W746884

2-Methyl-2-butenyl (E)-Caffeate	Cholinesterase (ChE)	Neurological Disease
2-Methyl-2-butenyl (E)-Caffeate is a type of caffeic acid ester compound. The petroleum ether and chloroform extracts containing 2-Methyl-2-butenyl (E)-Caffeate have inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The ether extract containing 2-Methyl-2-butenyl (E)-Caffeate exhibits strong antioxidant properties. 2-Methyl-2-butenyl (E)-Caffeate can be used in the research of Alzheimer's disease .

HY-N13189

cis-N-(4-Hydroxystyryl)benzamide	Others	Cardiovascular Disease
cis-N-(4-Hydroxystyryl)benzamide is a platelet aggregation inhibitor that can be isolated from the chloroform extract of Houttuynia cordata, a traditional Chinese medicine .

HY-N18049

Decussatin	Amylases	Metabolic Disease
Decussatin is an α-Amylases inhibitor isolated from the Tibetan medicinal plant Swertia mussotii. By inhibiting the catalytic activity of α-Amylases, Decussatin reduces the hydrolysis of complex carbohydrates such as starch and the intestinal absorption of glucose, thereby lowering blood glucose levels in the body. Decussatin shows no significant in vitro antibacterial or antifungal activity. Decussatin can be used for the research of type 2 diabetes .

6-Prenylapigenin 6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin	Structural Classification Flavonoids Flavones Maclura pomifera (Raf.) Schneid. Plants Moraceae Source Classification	Others
6-Prenylapigenin (6-Prenyl-4',5,7-trihydroxyflavone; 6-C-Prenylapigenin) is a prenylated flavonoid that exists in the stems and leaves of Maclura pomifera. 6-Prenylapigenin exhibits cytotoxicity against cancer cells such as leukemia cells and solid tumor cells .

3,7,25-Trihydroxycucurbita-5,23-dien-19-al TCD	Triterpenes Structural Classification Anthocyans Flavonoids Terpenoids Cucurbitaceae Plants Momordica charantia Linn. Source Classification	Drug Derivative
3,7,25-Trihydroxycucurbita-5,23-dien-19-al (TCD) is a natural product, that can be isolated from the chloroform extract of the leaves of Momordica foetida .

Volvalerenal E	Terpenoids Sesquiterpenes Valeriana officinalis Linn. Plants Valerianaceae Source Classification	Others
Volvalerenal E is an active product that can be isolated from a chloroform extract of the roots of Valeriana officinalis var. latifolia. .

Neobritannilactone B	Zingiber officinale Roscoe Terpenoids Sesquiterpenes Plants Source Classification Zingiberaceae	Others
Neobritannilactone B, a sesquiterpene, can be isolated from the chloroform fraction of the I. britannica. Neobritannilactone B is cytotoxic. Other extracts of I. britannica are also Dihydrofolate reductase (DHFR) inhibitors, which inhibit Shigella dysenteriae type 1 .

Hypercalin B	Natural Products Hypericum acmosepalum N. Robson Hypericaceae Plants Source Classification	Bacterial
Hypercalin B is an antibacterial agent that can be isolated from the hexane and chloroform extracts of the plant Hypericum acmosepalum. Hypercalin B exhibits inhibitory activity against multidrug-resistant strains of Staphylococcus aureus, with a MIC range of 0.5-128 mg/L .

2-Methyl-2-butenyl (E)-Caffeate	Structural Classification Animals Phenols Polyphenols Source Classification	Cholinesterase (ChE)
2-Methyl-2-butenyl (E)-Caffeate is a type of caffeic acid ester compound. The petroleum ether and chloroform extracts containing 2-Methyl-2-butenyl (E)-Caffeate have inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The ether extract containing 2-Methyl-2-butenyl (E)-Caffeate exhibits strong antioxidant properties. 2-Methyl-2-butenyl (E)-Caffeate can be used in the research of Alzheimer's disease .

cis-N-(4-Hydroxystyryl)benzamide	Monophenols Saururaceae Houttuynia cordata Thunb. Phenols Plants Source Classification	Others
cis-N-(4-Hydroxystyryl)benzamide is a platelet aggregation inhibitor that can be isolated from the chloroform extract of Houttuynia cordata, a traditional Chinese medicine .

Decussatin	Structural Classification Monophenols Gentianaceae Phenols Swertia mussotii Franch. Plants Source Classification	Amylases
Decussatin is an α-Amylases inhibitor isolated from the Tibetan medicinal plant Swertia mussotii. By inhibiting the catalytic activity of α-Amylases, Decussatin reduces the hydrolysis of complex carbohydrates such as starch and the intestinal absorption of glucose, thereby lowering blood glucose levels in the body. Decussatin shows no significant in vitro antibacterial or antifungal activity. Decussatin can be used for the research of type 2 diabetes .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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chloroform extracts

Inhibitors & Agonists

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Natural
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