20882-69-3
Chemical Structure
Decussatin
- CAS No.: 20882-69-3
- Formula:C16H14O6
- Molecular Weight:302.28
InChIKey: VYRIGRQQKUZPEX-UHFFFAOYSA-N
SMILES: O=C1C2=C(OC3=CC=C(C(OC)=C13)OC)C=C(OC)C=C2O
Biological Activity: Decussatin is an α-Amylases inhibitor isolated from the Tibetan medicinal plant Swertia mussotii. By inhibiting the catalytic activity of α-Amylases, Decussatin reduces the hydrolysis of complex carbohydrates such as starch and the intestinal absorption of glucose, thereby lowering blood glucose levels in the body. Decussatin shows no significant in vitro antibacterial or antifungal activity. Decussatin can be used for the research of type 2 diabetes[1][2][3].
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Decussatin | Decussatin is an α-Amylases inhibitor isolated from the Tibetan medicinal plant Swertia mussotii. By inhibiting the catalytic activity of α-Amylases, Decussatin reduces the hydrolysis of complex carbohydrates such as starch and the intestinal absorption of glucose, thereby lowering blood glucose levels in the body. Decussatin shows no significant in vitro antibacterial or antifungal activity. Decussatin can be used for the research of type 2 diabetes. | |||||||||||||||||||||
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- [1]. Alaribe C S, et al. Antimicrobial activities of hexane extract and decussatin from stembark extract of Ficus congensis[J]. International journal of molecular sciences, 2011, 12(4): 2750-2756.
- [2]. Olubomehin O O, et al. In vivo and in vitro anti-diabetic activity of extracts of Anthoclestia vogelii Planch and isolation of Decussatin, a new α-amylase inhibitor from its stem bark and leaves[J]. Nigerian Journal of Biochemistry and Molecular Biology, 2022, 37(1): 9-16.
- [3]. Jia J, et al. Preparative separation of methylswertianin, swerchirin and decussatin from the Tibetan medicinal plant Swertia mussotii using high-speed counter-current chromatography. Phytochem Anal. 2012;23(4):332-336. [Content Brief]
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