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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
cholestane
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "cholestane" in MCE Product Catalog:
1
Cat. No.: HY-133966
CAS No.: 41083-73-2
Synonyms: 5α-cholestane-3β,6α-diol
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6α-Hydroxy-5α-cholestane (5α-Cholestane-3β,6α-diol) is an oxysterol that promotes the production of superoxide anions in SK-N-BE cells at concentrations of 50 μM and 100 μM .
Cat. No.: HY-W010934
CAS No.: 1253-84-5
Cat. No.: HY-133970R
CAS No.: 481-21-0
Cat. No.: HY-133970S1
CAS No.: 122241-86-5
Cat. No.: HY-171949
CAS No.: 18866-87-0
Synonyms: 3α,7α,12α,25-Tetrahydroxycoprostane
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5β-Cholestane-3α,7α,12α,25-tetrol (3α,7α,12α,25-Tetrahydroxycoprostane) is a bile acid alcohol. 5β-Cholestane-3α,7α,12α,25-tetrol is a GPBAR1 (also known as TGR5) activator (EC50: 1.36 μM). 5β-Cholestane-3α,7α,12α,25-tetrol is the predominant bile-alcohol disease marker present in patients with Cerebrotendinous xanthomatosis (CTX) .
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Alkaloids Piperidine Alkaloids Microorganisms Pyrrole Alkaloids Solanum tuberosum Linn. Plants Solanaceae Disease Research Fields Cancer
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Cat. No.: HY-157161
11β-HSD2-IN-1 (compound CDSN) is a potent inhibitor of 11β-HSD2, inhibiting the metabolism of Cholestane-3β,5α,6β-triol (CT) in cells by 11β-HSD2 into the tumor promoter, carcinosterone. 11β-HSD2-IN-1 inhibits testosterone biosynthesis, thereby inhibiting MCF-7 cell proliferation. 11β-HSD2-IN-1 has immune activity and antiviral infection effects .
Cat. No.: HY-W127488
CAS No.: 481-20-9
Synonyms: Coprostane
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Cat. No.: HY-E71945
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5β-Cholestane-3α,7α-diol 12α-hydroxylase (EC 1.14.13.96) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert 5beta-cholestane-3alpha,7alpha-diol, reduced [NADPH--hemoprotein reductase] and O2 into 5beta-cholestane-3alpha,7alpha,12alpha-triol, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 2: convert 7alpha-hydroxycholest-4-en-3-one, reduced [NADPH--hemoprotein reductase] and O2 into 7alpha,12alpha-dihydroxycholest-4-en-3-one, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 3: convert chenodeoxycholate, reduced [NADPH--hemoprotein reductase] and O2 into cholate, oxidized [NADPH--hemoprotein reductase], H2O and H +.
Cat. No.: HY-E72010
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7α-Hydroxycholest-4-en-3-one 12α-hydroxylase (EC 1.14.18.8) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert 5beta-cholestane-3alpha,7alpha-diol, reduced [NADPH--hemoprotein reductase] and O2 into 5beta-cholestane-3alpha,7alpha,12alpha-triol, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 2: convert 7alpha-hydroxycholest-4-en-3-one, reduced [NADPH--hemoprotein reductase] and O2 into 7alpha,12alpha-dihydroxycholest-4-en-3-one, oxidized [NADPH--hemoprotein reductase], H2O and H +; reaction 3: convert chenodeoxycholate, reduced [NADPH--hemoprotein reductase] and O2 into cholate, oxidized [NADPH--hemoprotein reductase], H2O and H +.
Cat. No.: HY-P82418
Synonyms: CYP27A1; CYP27; Sterol 26-hydroxylase; mitochondrial; 5-beta-cholestane-3-alpha; 7-alpha; 12-alpha-triol 27-hydroxylase; Cytochrome P-450C27/25; Cytochrome P450 27; Sterol 27-hydroxylase; Vitamin D(3) 25-hydroxylase
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
