481-21-0
481-21-0
Chemical Structure
5α-Cholestane
- CAS No.: 481-21-0
- Formula:C27H48
- Molecular Weight:372.67
IUPAC Name: (5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene
InChIKey: XIIAYQZJNBULGD-XWLABEFZSA-N
SMILES: CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])CCCC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Activity: 5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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5α-Cholestane | 99.34% | 5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy. | ||||||||||||||||||||
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5α-Cholestane (Standard) | ≥98% | 5α-Cholestane (Standard) is the analytical standard of 5α-Cholestane (HY-133970). This product is intended for research and analytical applications. 5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy. | ||||||||||||||||||||
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α-Cholestane-d4 | 99% | α-Cholestane-d4 is the deuterium labeled α-Cholestane. | ||||||||||||||||||||
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5α-Cholestane-d6 | 99.78% | 5α-Cholestane-d6 is the deuterated-labeled 5α-Cholestane (HY-133970). 5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy. | ||||||||||||||||||||
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5α-Cholestane-d2 | 5α-Cholestane-d2 is the deuterated-labeled 5α-Cholestane (HY-133970). 5α-Cholestane is a steroidal hydrocarbon and fecal stanol, and is used as an internal standard for gas chromatographic sterol analysis. 5α-Cholestane is the parent steroidal skeleton of polyhydroxylated brassinosteroids of plant origin. It is used as an internal standard for GC-FID and GC-MS analysis of fecal sterols in urine and sludge samples. 5α-Cholestane can be used in studies of age- or disease-related skeletal muscle atrophy. | |||||||||||||||||||||
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5α-Cholestan-3β-ol | 99.92% | 5α-Cholestan-3β-ol is a derivitized steroid compound. | ||||||||||||||||||||
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5α-Cholestan-3-one | 99.92% | 5α-Cholestan-3-one is an endogenous metabolite. | ||||||||||||||||||||
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Coprostanol (Standard) | ≥98% | Coprostanol (5β-Cholestan-3β-ol) (Standard) is the analytical standard of Coprostanol. This product is used for research and analytical applications. Coprostanol is a fecal sterol formed by the reduction of cholesterol by microorganisms in the human and higher animal intestines. Coprostanol can be used as an indicator sterol for fecal contamination. Coprostanol has been recognized as a good indicator of water resource pollution caused by sewage discharge. Coprostanol can serve as a potential biological indicator for cerebral chondrodystrophy (CTX). | ||||||||||||||||||||
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5β-Cholane | 5β-Cholane is a farnesoid X receptor (FXR) activator. 5β-Cholane can be used for the research of cholesterol and lipid-related diseases. | |||||||||||||||||||||
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25-Azacoprostane | 25-Azacoprostane (5β-Cholan-24-dimethylamine) is an azasteroid. 25-Azacoprostane has significant inhibitory activity against the molting and metamorphosis processes of various insects. 25-Azacoprostane can be used as insecticide. | |||||||||||||||||||||
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3α-Aminocholestane | 98.0% | 3α-Aminocholestane is a selective SH2 domain-containing inositol-5′-phosphatase 1 (SHIP1) inhibitor with an IC50 of ~2.5 μM. | ||||||||||||||||||||
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Stigmastane | Stigmastane is a natural product that can be found in soybeans. | |||||||||||||||||||||
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5β-Cholestane | 5β-Cholestane is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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Epicoprostanol | 99.88% | Epicoprostanol is the compound found in adipocere. | ||||||||||||||||||||
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Coprostanone | 98.25% | Coprostanone (5β-cholestan-3-one) is an oxysterol and active metabolite of Cholesterol (HY-N0322). Coprostanone induces apoptosis in primary dog gallbladder epithelial cells. Coprostanone is promising for research of colon cancers or adenomatous polyps. | ||||||||||||||||||||
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References
- [1]. Esposito D, et al. Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. Journal of medicinal chemistry. 2011 Jun 23;54(12):4057-66. [Content Brief]
- [2]. Schönning C, et al. Faecal contamination of source-separated human urine based on the content of faecal sterols. Water research. 2002 Apr;36(8):1965-72. [Content Brief]
