18 Results for "

cucurbitane-type

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "cucurbitane-type" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-122949
CAS No.: 91590-76-0
Purity:  ≥97.0%
Momordicine I is a cucurbitane-type triterpenoids. Momordicine I suppresses glioma growth by promoting apoptosis and impairing mitochondrial oxidative phosphorylation. Momordicine I inhibits glycolysis, lipid metabolism, induces autophagy in HNC cells to suppress head and neck cancer growth. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ. Momordicine I exerts its cardiovascular benefits by upregulating nitric oxide, inhibiting the activity of angiotensin-converting enzyme (ACE), activating the PI3K/Akt pathway, reducing oxidative stress and inflammation. Momordicine I inhibits AKT1, IL-6, and SRC, suggesting its potential application in type 2 diabetes .
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Cat. No.: HY-N8410
CAS No.: 1011726-62-7
Momordicoside P is a cucurbitane-type triterpenoid saponin. Momordicoside P can be isolated from the fresh fruits of Momordica charantia .
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Cat. No.: HY-N6928
CAS No.: 88901-37-5
Mogroside III-E is a cucurbitane-type triterpenoid glycoside extracted from Siraitia grosvenorii, and it is an orally active TLR4 inhibitor. Mogroside III-E downregulates the expression of TLR4 and MyD88, and blocks the phosphorylation of downstream ERK, JNK and p38 MAPK molecules; meanwhile, it inhibits TGF-β- or LPS-mediated transdifferentiation of primary pulmonary fibroblasts into myofibroblasts, reduces the content of fibrosis markers such as hydroxyproline, suppresses the pro-fibrotic TGF-β/Smad signaling pathway, and downregulates the levels of inflammatory factors MPO and IL-1β. Mogroside III-E alleviates Bleomycin (HY-108345)-induced pulmonary collagen deposition and inflammatory infiltration in mice. Mogroside III-E can be used in studies related to idiopathic pulmonary fibrosis .
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Cat. No.: HY-N10672
CAS No.: 191097-54-8
Kuguacin R is a cucurbitane-type triterpenoid that can be extracted from Momordica charantia L. Kuguacin R possess anti-inflammatory, antimicrobial and anti-viral activities .
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Cat. No.: HY-N12473
CAS No.: 1135141-77-3
25-Deacetylcucurbitacin A is a Cucurbitane-Type triterpenoid and has the potential to be an anti-cancer agent and JAK/STAT3 signaling pathway inhibitor .
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Cat. No.: HY-N3248
CAS No.: 81371-54-2
Synonyms: Momordicacoside G
Momordicoside G (Momordicacoside G) is an orally active cucurbitane-type triterpene glycoside. Momordicoside G selectively induces apoptosis of M1-like macrophages, without affecting M2-like macrophages. Momordicoside G reduces intracellular ROS levels and promotes autophagy. Momordicoside G also has anticancer activity, inhibiting the growth of cancer cell lines. Momordicoside G stimulates M2-associated lung injury repair and prevents inflammatory lung cancer injury .
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Cat. No.: HY-108271
CAS No.: 88901-42-2
Purity:  99.10%
Mogroside III-A1 is a cucurbitane-type triterpene glycoside found in the fruit of Siraitia grosvenorii (monk fruit) .
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Cat. No.: HY-N8987
CAS No.: 1446447-97-7
(3β,7β)-3,7,23,24-Tetrahydroxycucurbita-5,25-dien-19-al (compound 3) is a cucurbitane-type triterpenoid isolated from the vines and leaves of Momordica charantia .
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Cat. No.: HY-N7620
CAS No.: 5942-25-6
Bryonamide B is a cucurbitane-type triterpenoid isolated from Bryonia aspera .
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Cat. No.: HY-111070
CAS No.: 934739-29-4
Karavilagenin D, a cucurbitane-type triterpene isolated from Japanese bitter melon leaves, is a potential tumor-promoting inhibitor .
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Cat. No.: HY-N6928R
CAS No.: 88901-37-5
Mogroside III-E (Standard) is the analytical standard of Mogroside III-E. This product is intended for research and analytical applications. Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, inhibits NO release, with anti-fibrotic activity .
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Cat. No.: HY-N10778
CAS No.: 1301267-02-6
(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol is a cucurbitane-type triterpenoid. (19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol has been tested to no effect against 5 cancer cell lines, MCF-7, HepG2, Du145, Colon205 and HL-60 by MTT assay .
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Cat. No.: HY-N18238
CAS No.: 476468-78-7
11-Oxomogroside I A1 is a cucurbitane-type triterpenoid glycoside and also an EBV-EA inhibitor. 11-Oxomogroside I A1 exerts 100% inhibitory effect on the induction of EBV-EA. 11-Oxomogroside I A1 can be used for cancer research .
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Cat. No.: HY-N17967
CAS No.: 916593-21-0
Grosmomoside I is a cucurbitane-type triterpene glycoside that can be isolated from the fruits of Momordica grosvenori .
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Cat. No.: HY-N20725
CAS No.: 29803-94-9
Cucurbitacin I 2-O-β-D-glucopyranoside is a cucurbitane-type triterpenoid glycoside. Cucurbitacin I 2-O-β-D-glucopyranoside can be isolated from the fruits of Citrullus colocynthis. Cucurbitacin I exhibits anti-tumor and anti-diabetic activities. Cucurbitacin I 2-O-β-D-glucopyranoside can be used in research related to cancer, inflammatory diseases and diabetes .
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Cat. No.: HY-N9885
CAS No.: 2081098-85-1
Xuedanencins D is a cucurbitane-type triterpenoid natural product without significant cytotoxicity against human cervical cancer HeLa cells (IC50 >100 μM). Xuedanencins D can be naturally extracted from the 95% ethanol extract of the tubers of Hemsleya penxianensis (a plant of the Hemsleya genus in the Cucurbitaceae family) .
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Cat. No.: HY-N9752
CAS No.: 942615-25-0
Mogroside II B is a cucurbitane-type glycoside with a sweet taste in water. Mogroside II B inhibits the activation of Epstein Barr virus early antigen (EBV-EA) induced by Phorbol 12-myristate 13-acetate (TPA) (HY-18739). Mogroside II B exerts weak inhibitory effects on the activation of the nitric oxide (NO) donor (NOR1) .
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Cat. No.: HY-N17638
CAS No.: 942612-72-8
7-Oxomogroside V is a cucurbitane-type glycoside isolated from the fruits of Siraitia grosvenorii. 7-Oxomogroside V inhibits the activation of Epstein-Barr virus early antigen (EBV-EA) induced by TPA (HY-18739). 7-Oxomogroside V also exerts weak inhibitory effects on the activation of the nitric oxide donor NOR 1. 7-Oxomogroside V is applicable to tumor-related research .
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