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Cat. No.: HY-N18238

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11-Oxomogroside I A1

11-Oxomogroside I A1 is a cucurbitane-type triterpenoid glycoside and also an EBV-EA inhibitor. 11-Oxomogroside I A1 exerts 100% inhibitory effect on the induction of EBV-EA. 11-Oxomogroside I A1 can be used for cancer research.

For research use only. We do not sell to patients.

CAS No.: 476468-78-7
Formula: C₃₆H₆₀O₉
Molecular Weight:636.86

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

11-Oxomogroside I A1 Chemical Structure

CAS No.: 476468-78-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

11-Oxomogroside I A1 (10-1×10³ mol ratio/TPA; 48 h) potently inhibits TPA-induced EBV-EA induction in Raji cells, achieving 100% inhibition at 1×10³ mol ratio/TPA while maintaining 70% cell viability, with decreasing inhibitory effects at lower mol ratios relative to TPA^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Immunofluorescence^[1]

Cell Line:

Raji cells (human lymphoblastoid cells carrying EBV genome)
Concentration:

10-1×10³ mol ratio/TPA
Incubation Time:

48 h
Result:

Reduced EBV-EA induction to 0% relative to the TPA-only positive control at 1×10³ mol ratio/TPA, with 70% Raji cell viability.
Reduced EBV-EA induction to 29.0% relative to the positive control at 500 mol ratio/TPA.
Reduced EBV-EA induction to 77.4% relative to the positive control at 100 mol ratio/TPA.
Reduced EBV-EA induction to 97.2% relative to the positive control at 10 mol ratio/TPA.

Chemical Information

CAS No. 476468-78-7
Molecular Weight 636.86
Formula C₃₆H₆₀O₉
SMILES

C[C@]12[C@@]3([H])[C@]([C@@]4([H])C(C(C)([C@H](CC4)O)C)=CC3)(C(C[C@@]1([C@@](CC2)([H])[C@H](C)CC[C@H](C(C)(O)C)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)C)=O)C
Structure Classification
- Terpenoids
- Tetracyclic Triterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ukiya M, et al. Inhibitory effects of cucurbitane glycosides and other triterpenoids from the fruit of Momordica grosvenori on epstein-barr virus early antigen induced by tumor promoter 12-O-tetradecanoylphorbol-13-acetate. J Agric Food Chem. 2002;50(23):6710-6715. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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