1 Result for "

eIF4A3-IN-18

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "eIF4A3-IN-18" in MCE Product Catalog:

Cat. No.: HY-148452
CAS No.: 1402931-84-3
Purity:  98.82%
Research Areas:  

Cancer

eIF4A3-IN-18 (compound 74) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-18 interferes the assembling of eIF4F translation complex with EC50 values of 0.8, 35 and 2 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-18 also has cytotoxicity to RMPI-8226 cells with an LC50 of 0.06 nM. eIF4A3-IN-18 can be used for the research of human cancer pathogenesis .
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